Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012713 | 0.86 | PIK3R1 (0.35) | PIK3R1PIK3CAMTORKDM4EHTT | |
| SCHEMBL5133875 | 0.84 | PIK3R1 (0.34) | PIK3R1PIK3CAMTORKDM4EHTT | |
| SCHEMBL5012716 | 0.84 | PIK3R1 (0.34) | PIK3R1PIK3CAMTORKDM4EHTT | |
| SCHEMBL5015619 | 0.84 | HRH3 (0.37) | PIK3R1PIK3CAMTORKDM4EHTT | |
| SCHEMBL5014333 | 0.84 | PIK3R1 (0.36) | PIK3R1PIK3CAMTORKDM4EHTT | |
| SCHEMBL5012742 | 0.84 | PIK3R1 (0.34) | PIK3R1PIK3CAMTORKDM4EHTT | |
| SCHEMBL5014366 | 0.83 | ALDH1A1 (0.43) | PIK3R1PIK3CAMTORKDM4EHTT | |
| SCHEMBL5010977 | 0.82 | KDM4E (0.33) | KDM4EHTTNPSR1TSHRHSD17B10 | |
| SCHEMBL5014390 | 0.81 | ALDH1A1 (0.41) | PIK3R1PIK3CAMTORKDM4EHTT | |
| SCHEMBL5014337 | 0.81 | KDM4E (0.35) | PIK3R1PIK3CAMTORKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |