Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016478 | 0.87 | CNR1 (0.52) | TSHRMEN1KMT2ATDP1TP53 | |
| SCHEMBL11499376 | 0.85 | L3MBTL1 (0.60) | TSHRMEN1KMT2ATDP1TP53 | |
| SCHEMBL5022978 | 0.84 | CNR1 (0.49) | TSHRMEN1KMT2ATDP1TP53 | |
| SCHEMBL30069272 | 0.83 | CNR1 (0.57) | TSHRMEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL23346286 | 0.81 | CNR1 (0.56) | TSHRMEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL30069294 | 0.81 | CNR1 (0.56) | TSHRMEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL10815702 | 0.78 | CNR1 (0.55) | TSHRMEN1KMT2ATDP1TP53 | |
| SCHEMBL5016181 | 0.78 | L3MBTL1 (0.54) | TSHRMEN1KMT2ATDP1TP53 | |
| SCHEMBL14174460 | 0.78 | CA12 (0.62) | CYP1A2CYP3A4CYP2C19KDM4EALDH1A1 | |
| SCHEMBL31006472 | 0.78 | IDO1 (0.52) | TSHRMEN1KMT2ATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365223-B2 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | NST NEUROSURVIVAL TECHNOLOGIES LTD (IL) | 2008-04-29 | — | — | US | disclosed |
| US-20060160901-A1 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | APOSENSE LTD. (IL) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160901-A1 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | BAD, BAX, CASP3 | TSHR 2988/4885MEN1 4258/4885KMT2A 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.