Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728064 | 0.79 | CA1 (0.31) | — | |
| SCHEMBL5086089 | 0.77 | ACHE (0.31) | TSHR | |
| SCHEMBL3670738 | 0.77 | TSHR (0.47) | TSHRHPGDHCAR2 | |
| SCHEMBL1229404 | 0.76 | ALDH1A1 (0.37) | TSHRHPGDHCAR2 | |
| Butadiene SCHEMBL8956976 | 0.76 | TSHR (0.44) | TSHRHPGDHCAR2 | |
| SCHEMBL8928327 | 0.75 | LCK (0.36) | — | |
| SCHEMBL9871522 | 0.74 | DNM1 (0.38) | TSHRHPGDHCAR2 | |
| SCHEMBL8425837 | 0.73 | TSHR (0.55) | TSHRHPGDHCAR2 | |
| SCHEMBL8430254 | 0.73 | TSHR (0.55) | TSHRHPGDHCAR2 | |
| SCHEMBL8003904 | 0.73 | CHRM1 (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660054-B1 | AGENT CONTAINING ERGOLIN FOR TRANSDERMAL APPLICATION | AXXONIS PHARMA AG (DE) | 2008-08-13 | — | — | EP | claimed |