Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.45 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 2/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288147 | 0.82 | CYP3A4 (0.52) | ADORA2AADORA1METTL3METTL14CYP3A4 | |
| SCHEMBL2904497 | 0.74 | ADORA2A (0.46) | ADORA2AADORA1METTL3METTL14PI4KA | |
| SCHEMBL2937354 | 0.74 | FAP (0.52) | ADORA2AADORA1METTL3METTL14CYP3A4 | |
| SCHEMBL3293432 | 0.73 | FGFR1 (0.47) | ADORA2AADORA1METTL3METTL14CYP3A4 | |
| SCHEMBL13328610 | 0.72 | CYP3A4 (0.50) | ADORA2AADORA1METTL3METTL14CYP3A4 | |
| SCHEMBL2904496 | 0.72 | FGFR1 (0.61) | ADORA2AADORA1METTL3METTL14CYP3A4 | |
| SCHEMBL3288510 | 0.72 | ADORA2A (0.47) | ADORA2AADORA1METTL3METTL14CYP3A4 | |
| SCHEMBL3005461 | 0.71 | ADORA2A (0.48) | ADORA2AADORA1METTL3METTL14PI4KA | |
| SCHEMBL3005457 | 0.71 | ADORA2A (0.48) | ADORA2AADORA1METTL3METTL14PI4KA | |
| SCHEMBL2913580 | 0.70 | CYP3A4 (0.50) | ADORA2AADORA1METTL3METTL14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-A4 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2008-03-05 | — | — | EP | disclosed |
| EP-1358198-A1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG Chem Investment, Ltd. (KR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002057288-A1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD. (KR) | 2002-07-25 | — | — | WO | disclosed |