Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 3/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dansylglycine SCHEMBL386439 | 0.84 | HDAC4 (0.60) | HDAC4HDAC10HDAC6HDAC5CYP1A2 | |
| Dansylglycine SCHEMBL31496395 | 0.84 | HDAC4 (0.60) | HDAC4HDAC10HDAC6HDAC5CYP1A2 | |
| SCHEMBL5016479 | 0.80 | TTR (0.47) | HDAC4HDAC10HDAC6HDAC5MEN1 | |
| Dansylglycine SCHEMBL28460517 | 0.78 | HDAC4 (0.54) | HDAC4HDAC10HDAC6HDAC5F2 | |
| SCHEMBL5015679 | 0.77 | CYP1A2 (0.47) | MEN1TP53CYP1A2CYP3A4TSHR | |
| SCHEMBL9751653 | 0.76 | HDAC4 (0.57) | HDAC4HDAC10HDAC6HDAC5CYP1A2 | |
| Dansylglycine SCHEMBL4273131 | 0.76 | HDAC4 (0.52) | HDAC4HDAC10HDAC6HDAC5TSHR | |
| SCHEMBL5016181 | 0.75 | L3MBTL1 (0.54) | MEN1TP53CYP1A2CYP3A4TSHR | |
| SCHEMBL17268647 | 0.74 | HDAC4 (0.63) | HDAC4HDAC10HDAC6HDAC5CYP1A2 | |
| SCHEMBL10002024 | 0.74 | HDAC4 (0.67) | HDAC4HDAC10HDAC6HDAC5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365223-B2 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | NST NEUROSURVIVAL TECHNOLOGIES LTD (IL) | 2008-04-29 | — | — | US | disclosed |
| US-20060160901-A1 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | APOSENSE LTD. (IL) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160901-A1 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | BAD, BAX, CASP3 | HDAC4 2044/4885HDAC10 3078/4885HDAC6 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.