Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5545716 | 0.82 | ALDH1A1 (0.44) | ALDH1A1GAAL3MBTL1SLC6A4AR | |
| SCHEMBL5545509 | 0.81 | AR (0.46) | ALDH1A1GAASLC6A4HTR2AAR | |
| SCHEMBL5536933 | 0.80 | DHFR (0.44) | ALDH1A1GAAL3MBTL1ARF10 | |
| SCHEMBL10545690 | 0.80 | L3MBTL1 (0.51) | L3MBTL1SLC6A4HTR2AKCNH2MAPT | |
| SCHEMBL2090486 | 0.76 | AR (0.43) | ALDH1A1L3MBTL1ARPOLBKDM4E | |
| SCHEMBL10550360 | 0.75 | ALDH1A1 (0.58) | ALDH1A1GAAL3MBTL1ARACHE | |
| SCHEMBL5537743 | 0.74 | ALDH1A1 (0.59) | ALDH1A1GAAL3MBTL1ARKDM4E | |
| SCHEMBL18328945 | 0.74 | HTR2A (0.50) | ALDH1A1L3MBTL1SLC6A4HTR2AKCNH2 | |
| SCHEMBL2091035 | 0.73 | HTT (0.53) | ALDH1A1GAAL3MBTL1ARF10 | |
| SCHEMBL10544322 | 0.73 | L3MBTL1 (0.44) | ALDH1A1GAAL3MBTL1SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |