SCHEMBL5016309

SCHEMBL5016309

C=C(C)C(=O)NC(=O)[C@@H](N)CCCCN

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.49
GNAO1 P09471 1/20 0.49
GNAI1 P63096 1/20 0.49
GSR P00390 1/20 0.47
DPP7 Q9UHL4 4/20 0.46
DPP8 Q6V1X1 2/20 0.46
DPP9 Q86TI2 2/20 0.46
SLC15A1 P46059 1/20 0.44
DPP4 P27487 1/20 0.40
MMP2 P08253 1/20 0.40
TLR2 O60603 2/20 0.39
RNPEP Q9H4A4 1/20 0.38
RRM1 P23921 1/20 0.37
TERT O14746 3/20 0.36
LTA4H P09960 1/20 0.36
SIRT6 Q8N6T7 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
CPB2 Q96IY4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6563762 0.95 SLC15A1 (0.45) GNAI3GNAO1GNAI1GSRDPP7
SCHEMBL10062328 0.83 GNAI3 (0.64) GNAI3GNAO1GNAI1GSRDPP7
SCHEMBL7294153 0.82 GNAI3 (0.54) GNAI3GNAO1GNAI1GSRDPP7
SCHEMBL5499007 0.82 GSR (0.61) GNAI3GNAO1GNAI1GSRDPP7
SCHEMBL29989156 0.81 GSR (0.57) GNAI3GNAO1GNAI1GSRDPP7
SCHEMBL5495401 0.80 GSR (0.59) GNAI3GNAO1GNAI1GSRDPP7
SCHEMBL4414228 0.78 DPP4 (0.49) GSRDPP8DPP9SLC15A1DPP4
SCHEMBL2969796 0.78 DPP4 (0.49) GSRDPP7DPP8DPP9SLC15A1
SCHEMBL28122346 0.78 GSR (0.44) GNAI3GNAO1GNAI1GSRDPP7
SCHEMBL29616781 0.77 SLC15A1 (0.50) GNAI3GNAO1GNAI1GSRDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240408027-A1 HIGH DRUG LOADING POLYMERS VANDERBILT UNIVERSITY 2024-12-12 US claimed
US-11912894-B2 Antimicrobial and antifouling conformal hydrogel coatings CORNELL UNIVERSITY (US) 2024-02-27 US claimed
US-11655343-B2 Alginate hydrogel compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-23 US claimed
WO-2023076220-A1 CONJUGATES HAVING ANTIFOULING NANOPARTICLES AND METHODS OF USE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-05-04 WO claimed
WO-2023059833-A1 HIGH DRUG LOADING POLYMERS VANDERBILT UNIVERSITY (US) 2023-04-13 WO claimed
US-20200172741-A1 ANTIMICROBIAL AND ANTIFOULING CONFORMAL HYDROGEL COATINGS CORNELL UNIVERSITY 2020-06-04 US claimed
US-20150274891-A1 MEMBRANES WITH IMPROVED FLUX AND METHOD FOR THEIR PREPARATION BASF SE (DE) 2015-10-01 US claimed
US-12338330-B2 Alginate hydrogel compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-06-24 US disclosed
WO-2025129139-A1 TRIBLOCK COPOLYMERS AND HYDROGELS THEREOF VANDERBILT UNIVERSITY (US) 2025-06-19 WO disclosed
US-20240408027-A1 HIGH DRUG LOADING POLYMERS VANDERBILT UNIVERSITY 2024-12-12 US disclosed
US-11912894-B2 Antimicrobial and antifouling conformal hydrogel coatings CORNELL UNIVERSITY (US) 2024-02-27 US disclosed
US-20230348675-A1 ALGINATE HYDROGEL COMPOSITIONS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-11-02 US disclosed
US-11655343-B2 Alginate hydrogel compositions TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-23 US disclosed
WO-2014095754-A1 FILTRATION SYSTEMS AND MEMBRANES WITH ENHANCED FLUX AND METHOD FOR THEIR PREPARATION BASF SE (DE) 2014-06-26 WO disclosed
WO-2014095753-A1 MEMBRANES WITH IMPROVED FLUX AND METHOD FOR THEIR PREPARATION BASF SE (DE) 2014-06-26 WO disclosed
WO-2014095749-A1 FILTRATION SYSTEMS AND MEMBRANES WITH ENHANCED FLUX AND METHOD FOR THEIR PREPARATION BASF SE (DE) 2014-06-26 WO disclosed
EP-1156031-B1 NOVEL COMPOUND, POLYMER PREPARED FROM THE COMPOUND, AND COMPOSITION COMPRISING THE POLYMER POLA CHEM IND INC (JP) 2008-09-17 EP disclosed
JP-2004137382-A WATER-ABSORBING COMPOSITION EHIME PREFECTURE 2004-05-13 JP disclosed
US-6703468-B1 COMPOSITION FOR TOPICAL ADMINISTRATION TO SKIN OR HAIR COMPRISING SUITABLE CARRIER AND EFFECTIVE AMOUNT OF SPECIFIED POLYMER WHICH HAS BENEFICIAL EFFECTS ON SKIN FUNCTIONS POLA CHEMICAL INDUSTRIES INC. (JP) 2004-03-09 US disclosed
EP-1156031-A1 NOVEL COMPOUND, POLYMER PREPARED FROM THE COMPOUND, AND COMPOSITION COMPRISING THE POLYMER POLA CHEMICAL INDUSTRIES, INC. (JP) 2001-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240408027-A1 HIGH DRUG LOADING POLYMERS ABCB1, ABCB11, FCGR2A GNAI3 3977/4885GNAO1 3553/4885GNAI1 3697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.