SCHEMBL501719

SCHEMBL501719

Cc1cccc(C([O])=O)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
HSD17B10 Q99714 3/20 0.48
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 2/20 0.48
HPGD P15428 2/20 0.48
KMT2A Q03164 3/20 0.47
CYP3A4 P08684 3/20 0.47
TRPA1 O75762 2/20 0.47
MEN1 O00255 2/20 0.47
LMNA P02545 2/20 0.47
CYP2C9 P11712 2/20 0.47
AKR1B10 O60218 1/20 0.47
ABCB11 O95342 1/20 0.47
DHFR P00374 1/20 0.47
MPO P05164 1/20 0.47
CYP1A2 P05177 1/20 0.47
CHRM1 P11229 1/20 0.47
AKR1B1 P15121 1/20 0.47
PTGS1 P23219 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL310386 0.83 KMT2A (0.52) ESR1ESR2HSD17B10ALDH1A1KDM4E
SCHEMBL9864607 0.83 ESR1 (0.52) ESR1ESR2HSD17B10ALDH1A1KDM4E
SCHEMBL29515031 0.83 KMT2A (0.52) ESR1ESR2HSD17B10ALDH1A1KDM4E
Benzene SCHEMBL27738764 0.81 KMT2A (0.55) ESR1ESR2HSD17B10ALDH1A1KDM4E
SCHEMBL31519420 0.81 ESR1 (0.50) ESR1ESR2HSD17B10ALDH1A1KDM4E
SCHEMBL29357094 0.81 ALDH1A1 (0.65) ESR1ESR2HSD17B10ALDH1A1KDM4E
SCHEMBL697259 0.81 ESR1 (0.50) ESR1ESR2HSD17B10ALDH1A1KDM4E
SCHEMBL56188 0.81 ALDH1A1 (0.65) ESR1ESR2HSD17B10ALDH1A1KDM4E
SCHEMBL49951 0.80 HPGD (0.52) HSD17B10ALDH1A1KDM4EHPGDKMT2A
SCHEMBL23079045 0.79 ESR1 (0.49) ESR1ESR2HSD17B10ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4795965-B2 2011-10-19 JP claimed
EP-1685102-A4 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD (KR) 2008-08-20 EP claimed
US-20070129346-A1 Melanocortin receptor agonists LG LIFE SCIENCES LTD. (KR) 2007-06-07 US claimed
JP-2007510717-A 2007-04-26 JP claimed
EP-1685102-A1 MELANOCORTIN RECEPTOR AGONISTS LG Life Sciences Ltd. (KR) 2006-08-02 EP claimed
WO-2005047251-A1 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD. (KR) 2005-05-26 WO claimed
EP-0649846-B1 Galanthamine derivates, a process for their preparation and their use as medicaments AVENTIS PHARMA INC (US) 2002-01-02 EP claimed
EP-0649846-A1 Galanthamine derivates, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1995-04-26 EP claimed
EP-0331593-B1 PROCESS FOR THE PREPARATION OF HYDROXYBENZALDEHYDES BY HYDROCARBONYLATION RHONE-POULENC CHIMIE (FR) 1992-11-25 EP claimed
EP-0351336-B1 PROCESS FOR THE PREPARATION OF HYDROXYBENZALDEHYDES BY HYDROCARBONYLATION RHONE-POULENC CHIMIE (FR) 1992-10-28 EP claimed
US-4933497-A Preparation of hydroxybenzaldehydes by hydrocarbonylation of halophenols RHONE-POULENC CHIMIE (FR) 1990-06-12 US claimed
EP-0351336-A1 Process for the preparation of hydroxybenzaldehydes by hydrocarbonylation RHONE-POULENC CHIMIE (FR) 1990-01-17 EP claimed
EP-0331593-A1 Process for the preparation of hydroxybenzaldehydes by hydrocarbonylation RHONE-POULENC CHIMIE (FR) 1989-09-06 EP claimed
WO-2024135508-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR AND SOLID-STATE IMAGING DEVICE 三菱瓦斯化学株式会社 2024-06-27 WO disclosed
CN-117957265-A Process for producing dihydroxy compound and process for producing regenerated resin 三菱瓦斯化学株式会社 2024-04-30 CN disclosed
CN-117916325-A Thermoplastic resin composition, molded article, method for producing thermoplastic resin composition, and method for improving transmittance 三菱瓦斯化学株式会社 2024-04-19 CN disclosed
US-4366316-A FROM OXAZOLINOAZETIDINONE AND ACID SHIONOGI & CO., LTD. (JP) 1982-12-28 US disclosed
US-4025401-A Method for diaphragm electrolysis of alkali metal halides MARUZEN OIL CO. LTD. (JA) 1977-05-24 US disclosed
US-4011147-A METHOD FOR DIAPHRAGM ELECTROLYSIS OF ALKALI METAL HALIDES MARUZEN OIL CO. LTD. (JA) 1977-03-08 US disclosed
US-3970534-A Graft copolymer and process for preparation thereof MARUZEN OIL CO. LTD. (JA) 1976-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129346-A1 Melanocortin receptor agonists MC1R, MC3R, MC5R ESR1 1296/4885ESR2 1467/4885HSD17B10 1389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.