Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29425530 | 0.81 | HPGD (0.54) | HPGDERCC5FEN1HTTTSHR | |
| SCHEMBL166603 | 0.81 | HPGD (0.54) | HPGDERCC5FEN1HTTTSHR | |
| SCHEMBL333141 | 0.81 | CYP3A4 (0.55) | HPGDERCC5FEN1KMT2AHTT | |
| SCHEMBL29387256 | 0.81 | CYP3A4 (0.55) | HPGDERCC5FEN1KMT2AHTT | |
| SCHEMBL501719 | 0.80 | ESR1 (0.50) | HPGDKMT2AHTTTSHRNPC1 | |
| SCHEMBL4652941 | 0.80 | ALDH1A1 (0.56) | HPGDTSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10669335 | 0.79 | CYP3A4 (0.59) | HPGDERCC5FEN1KMT2AHTT | |
| Toluic Acid SCHEMBL148201 | 0.79 | ALDH1A1 (0.65) | HPGDERCC5FEN1KMT2ASMN1; SMN2 | |
| SCHEMBL112406 | 0.79 | HPGD (0.57) | HPGDERCC5FEN1HTTNPC1 | |
| Toluic Acid SCHEMBL4152 | 0.79 | ALDH1A1 (0.65) | HPGDERCC5FEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4265602-A2 | LEOLIGIN DERIVATIVES AS PROLIFERATION INHIBITORS OF SMOOTH MUSCLE CELLS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2023-10-25 | — | — | EP | claimed |
| EP-2697206-B1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF IN THE TREATMENT OF SEXUAL DISORDERS | ATIR HOLDING S A (LU) | 2019-04-03 | — | — | EP | claimed |
| US-20170157301-A1 | LEOLIGIN DERIVATIVES AS SMOOTH MUSCLE CELL PROLIFERATION INHIBITORS | TECHNISCHE UNIVERSITÄET WIEN (AT) | 2017-06-08 | — | — | US | claimed |
| EP-3160462-A1 | LEOLIGIN DERIVATIVES AS SMOOTH MUSCLE CELL PROLIFERATION INHIBITORS | Technische Universität Wien (AT) | 2017-05-03 | — | — | EP | claimed |
| WO-2015196228-A1 | LEOLIGIN DERIVATIVES AS SMOOTH MUSCLE CELL PROLIFERATION INHIBITORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2015-12-30 | — | — | WO | claimed |
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-12 | — | — | US | claimed |
| EP-2892343-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2015-07-15 | — | — | EP | claimed |
| WO-2014037349-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2014-03-13 | — | — | WO | claimed |
| US-20110184173-A1 | Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity | THE KITASATO INSTITUTE (JP) | 2011-07-28 | — | — | US | claimed |
| EP-2228376-A1 | PYRIPYROPENE DERIVATIVE HAVING ACAT2-INHIBITING ACTIVITY | The Kitasato Institute (JP) | 2010-09-15 | — | — | EP | claimed |
| EP-0351336-B1 | PROCESS FOR THE PREPARATION OF HYDROXYBENZALDEHYDES BY HYDROCARBONYLATION | RHONE-POULENC CHIMIE (FR) | 1992-10-28 | — | — | EP | claimed |
| US-5101032-A | Sensitizers for photopolymerization and electrography | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | claimed |
| US-4933497-A | Preparation of hydroxybenzaldehydes by hydrocarbonylation of halophenols | RHONE-POULENC CHIMIE (FR) | 1990-06-12 | — | — | US | claimed |
| EP-0351336-A1 | Process for the preparation of hydroxybenzaldehydes by hydrocarbonylation | RHONE-POULENC CHIMIE (FR) | 1990-01-17 | — | — | EP | claimed |
| EP-0331593-A1 | Process for the preparation of hydroxybenzaldehydes by hydrocarbonylation | RHONE-POULENC CHIMIE (FR) | 1989-09-06 | — | — | EP | claimed |
| US-4291047-A | Combating fungi with α-azolyl-β-hydroxy-ketones | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-22 | — | — | US | claimed |
| EP-0004727-B1 | BLOOD PLATELET AGGREGATION INHIBITORY PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESSES FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-12 | — | — | EP | claimed |
| US-4268510-A | DEMETHANIZATION, METABOLISM, RUMEN | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-19 | — | — | US | claimed |
| EP-0010348-A1 | Heterocyclic trichloromethyl derivatives, process for their preparation and their use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | claimed |
| EP-0004727-A2 | Blood platelet aggregation inhibitory pyridine derivatives, pharmaceutical compositions thereof, and processes for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-10-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | CAT, HSF1, HPD | HPGD 205/4885ERCC5 3637/4885FEN1 3593/4885 |
| US-20110184173-A1 | Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity | ACAT2, ACAT1, AGPAT2 | HPGD 1060/4885ERCC5 4866/4885FEN1 3500/4885 |
| US-20170157301-A1 | LEOLIGIN DERIVATIVES AS SMOOTH MUSCLE CELL PROLIFERATION INHIBITORS | CCNH, MYLK, CCAR2 | HPGD 2024/4885ERCC5 2546/4885FEN1 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.