SCHEMBL697259

SCHEMBL697259

CC(=O)c1cccc(C)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
BRPF1 P55201 1/20 0.48
ALDH1A1 P00352 4/20 0.48
HSD17B10 Q99714 3/20 0.48
HPGD P15428 3/20 0.48
KDM4E B2RXH2 3/20 0.48
LMNA P02545 3/20 0.47
KMT2A Q03164 3/20 0.47
TRPA1 O75762 2/20 0.47
MEN1 O00255 2/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2C9 P11712 2/20 0.47
AKR1B10 O60218 1/20 0.47
ABCB11 O95342 1/20 0.47
DHFR P00374 1/20 0.47
MPO P05164 1/20 0.47
CYP1A2 P05177 1/20 0.47
CHRM1 P11229 1/20 0.47
AKR1B1 P15121 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31519420 1.00 ESR1 (0.50) ESR1ESR2BRPF1ALDH1A1HSD17B10
SCHEMBL29515031 0.83 KMT2A (0.52) ESR1ESR2ALDH1A1HSD17B10HPGD
SCHEMBL310386 0.83 KMT2A (0.52) ESR1ESR2ALDH1A1HSD17B10HPGD
SCHEMBL9864607 0.83 ESR1 (0.52) ESR1ESR2ALDH1A1HSD17B10HPGD
SCHEMBL29407046 0.81 TRPA1 (0.46) ESR1ESR2ALDH1A1HSD17B10HPGD
SCHEMBL29357094 0.81 ALDH1A1 (0.65) ESR1ESR2ALDH1A1HSD17B10HPGD
SCHEMBL25550174 0.81 MYC (0.44) BRPF1ALDH1A1HSD17B10HPGDKDM4E
SCHEMBL501719 0.81 ESR1 (0.50) ESR1ESR2ALDH1A1HSD17B10HPGD
SCHEMBL715998 0.81 TRPA1 (0.46) ESR1ESR2ALDH1A1HSD17B10HPGD
SCHEMBL56188 0.81 ALDH1A1 (0.65) ESR1ESR2ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023115621-A1 METHOD FOR PREPARING Α-HALOGENATED ACETOPHENONE COMPOUND UNDER CATALYSIS OF IONIC LIQUID [TEA][TFOH]2 大连大学 2023-06-29 WO claimed
CN-115028519-A Novel synthesis method of dexmedetomidine intermediate 2, 3-dimethylacetophenone 南京亿华药业有限公司 2022-09-09 CN claimed
CN-114181088-A Ionic liquid (TEA)][TfOH]2Method for preparing alpha-halogenated acetophenone compounds by catalysis 大连大学 2022-03-15 CN claimed
US-12522696-B2 Bisphenol composition and polycarbonate resin MITSUBISHI CHEMICAL CORPORATION (JP) 2026-01-13 US disclosed
US-12215189-B2 Bisphenol composition and polycarbonate resin MITSUBISHI CHEMICAL CORPORATION (JP) 2025-02-04 US disclosed
CN-115968391-B Composition, resin, method for producing amorphous film, method for forming resist pattern, method for producing underlayer film for lithography, and method for forming circuit pattern 三菱瓦斯化学株式会社 2024-04-26 CN disclosed
CN-112218844-B Compound, resin, composition, resist pattern forming method, circuit pattern forming method, and resin purifying method 三菱瓦斯化学株式会社 2024-04-26 CN disclosed
US-20240117102-A1 POLYMER, COMPOSITION, METHOD FOR PRODUCING POLYMER, COMPOSITION FOR FILM FORMATION, RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, RADIATION-SENSITIVE COMPOSITION, COMPOSITION FOR UNDERLAYER FILM FORMATION FOR LITHOGRAPHY, METHOD FOR PRODUCING UNDERLAYER FILM FOR LITHOGRAPHY, CIRCUIT PATTERN FORMATION METHOD, AND COMPOSITION FOR OPTICAL MEMBER FORMATION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-04-11 US disclosed
US-20240117101-A1 COMPOSITION FOR FILM FORMATION, RESIST COMPOSITION, RADIATION-SENSITIVE COMPOSITION, METHOD FOR PRODUCING AMORPHOUS FILM, RESIST PATTERN FORMATION METHOD, COMPOSITION FOR UNDERLAYER FILM FORMATION FOR LITHOGRAPHY, METHOD FOR PRODUCING UNDERLAYER FILM FOR LITHOGRAPHY, CIRCUIT PATTERN FORMATION METHOD, COMPOSITION FOR OPTICAL MEMBER FORMATION, RESIN FOR UNDERLAYER FILM FORMATION, RESIST RESIN, RADIATION-SENSITIVE RESIN, AND RESIN FOR UNDERLAYER FILM FORMATION FOR LITHOGRAPHY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-04-11 US disclosed
CN-113574042-B Bisphenol composition and polycarbonate resin 三菱化学株式会社 2023-10-13 CN disclosed
CN-113574041-B Bisphenol production method and polycarbonate resin production method 三菱化学株式会社 2023-10-13 CN disclosed
CN-1434834-A Photocurable composition and method for producing the same, photocurable pressure-sensitive adhesive sheet and method for producing the same, and method for bonding SEKISUI CHEMICAL CO LTD (JP) 2003-08-06 CN disclosed
US-20030139600-A1 2-pyridylsilane, processes for producing and using the same SUMITOMO CHEMICAL CO., LTD. 2003-07-24 US disclosed
US-6548673-B1 Alkylation using transition metal complex catalyst; purified by acid/base extraction SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-15 US disclosed
US-6531602-B2 Desilylation of a 2-pyridylsilane to form an alcohol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-11 US disclosed
US-20020165397-A1 2-Pyridylsilane, processes for producing and using the same SUMITOMO CHEMICAL CO., LTD. 2002-11-07 US disclosed
EP-1035125-A2 2-Pyridylsilane, processes for producing and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-13 EP disclosed
CN-1041415-C 3-arylbenzofuranone stabilizers and uses thereof CIBA GEIGY AG (CH) 1998-12-30 CN disclosed
CN-1074909-A UVA-absorbing sunscreen metal complexes RICHARDSON VICKS INC (US) 1993-08-04 CN disclosed
EP-0164593-B1 ANTI-INFLAMMATORY PHTHALAZINONES FISONS CORPORATION (US) 1989-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165397-A1 2-Pyridylsilane, processes for producing and using the same H1-0, RIOK2, H1-4 ESR1 4502/4885ESR2 3867/4885BRPF1 460/4885
US-12215189-B2 Bisphenol composition and polycarbonate resin SUZ12, RB1, RRP12 ESR1 71/4885ESR2 36/4885BRPF1 81/4885
US-20030139600-A1 2-pyridylsilane, processes for producing and using the same H1-0, H1-4, H1-2 ESR1 4521/4885ESR2 3952/4885BRPF1 394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.