SCHEMBL575145

SCHEMBL575145

CCCCP(=O)(OCC)OCC

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 1/20 0.58
TSHR P16473 2/20 0.55
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28769431 0.93 PPARD (0.52) PPARDTSHR
SCHEMBL388266 0.92 PPARD (0.56) PPARDTSHR
SCHEMBL575326 0.91 PPARD (0.50) PPARDTSHRCYP3A4
SCHEMBL1296192 0.91 CYP3A4 (0.54) PPARDTSHRCYP3A4
SCHEMBL2941289 0.90 PPARD (0.54) PPARDTSHR
SCHEMBL2185289 0.90 PPARD (0.54) PPARDTSHR
SCHEMBL11271012 0.90 PPARD (0.54) PPARDTSHR
SCHEMBL11275301 0.90 PPARD (0.54) PPARDTSHR
SCHEMBL3980817 0.90 PPARD (0.54) PPARDTSHR
SCHEMBL503511 0.90 PPARD (0.54) PPARDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120122763-A1 NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS AETERNA ZENTARIS GMBH (DE) 2012-05-17 US claimed
CN-101205268-B Method for hydrogenating conjugated diene polymer and hydrogenation catalyst composition TSRC CORP 2010-09-29 CN claimed
EP-2150558-A1 NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS AEterna Zentaris GmbH (DE) 2010-02-10 EP claimed
US-20090170783-A1 NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS AETERNA ZENTARIS GMBH (DE) 2009-07-02 US claimed
WO-2008132153-A1 NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS ÆTERNA ZENTARIS GMBH (DE) 2008-11-06 WO claimed
EP-1988098-A1 Novel Tetrahydrocarbazole Derivatives as Ligands of G-protein Coupled Receptors AEterna Zentaris GmbH (DE) 2008-11-05 EP claimed
CN-101205268-A Method for hydrogenating conjugated diene polymer and hydrogenation catalyst composition TSRC CORP (CN) 2008-06-25 CN claimed
EP-0133680-B1 METHOD OF PRODUCING COMPRESSION-MOULDED MATERIALS USING POLYISOCYANATE BINDING AGENTS CONTAINING LATENT, HEAT-ACTIVATABLE CATALYSTS BAYER AG (DE) 1988-04-27 EP claimed
CN-119176837-A Self-assembled hole transport material and application thereof 昆山协鑫光电材料有限公司 2024-12-24 CN disclosed
CN-119176836-A Preparation method and application of self-assembled hole transport material 昆山协鑫光电材料有限公司 2024-12-24 CN disclosed
CN-118755057-A Hole-transporting polymer material, preparation method and application 昆山协鑫光电材料有限公司 2024-10-11 CN disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-20240297344-A1 NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-05 US disclosed
CN-110922437-B Glucose compound, pharmaceutical composition and application thereof 凯惠科技发展(上海)有限公司 2023-11-03 CN disclosed
EP-0013744-B1 CATALYST AND PROCESS FOR THE POLYMERIZATION OF ALPHA-OLEFINS AND A PROCESS FOR PREPARING AN ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT Standard Oil Company (US) 1984-11-07 EP disclosed
EP-0120981-A1 Resin encapsulation type semiconductor device KABUSHIKI KAISHA TOSHIBA (JP) 1984-10-10 EP disclosed
EP-0102482-A2 Process for producing polyisocyanates containing isocyanurate groups, and their use as isocyanate components for producing polyurethanes BAYER AG (DE) 1984-03-14 EP disclosed
US-4233182-A High activity catalyst for the polymerization of alpha-olefins STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
EP-0013744-A1 Catalyst and process for the polymerization of alpha-olefins and a process for preparing an alpha-olefin polymerization catalyst component Standard Oil Company (US) 1980-08-06 EP disclosed
EP-0000024-A1 Polyadducts containing phosphorus and their application in the flameproofing of textile materials HOECHST AKTIENGESELLSCHAFT (DE) 1978-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170783-A1 NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS GPR88, GPR34, GPR27 PPARD 213/4885TSHR 498/4885CYP3A4 1753/4885
US-20120122763-A1 NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS GPR88, GPR34, GPR27 PPARD 213/4885TSHR 498/4885CYP3A4 1753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.