SCHEMBL5017375

SCHEMBL5017375

CCc1cc(Oc2cc(CC)c(O)c(CC)c2)cc(CC)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
DHFR P00374 1/20 0.36
LTA4H P09960 3/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
ITGB3 P05106 1/20 0.34
ITGAV P06756 1/20 0.34
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
RXRA P19793 1/20 0.34
PPARG P37231 1/20 0.34
MAOA P21397 1/20 0.34
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
BCL2 P10415 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20102180 0.89 DHFR (0.43) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL15033132 0.88 PRKCE (0.44) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL16520304 0.83 CYP1A2 (0.36) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL5078639 0.83 GABRA1 (0.46) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL25329709 0.81 GABRA1 (0.44) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL13057610 0.79 CYP3A4 (0.47) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL25328339 0.78 GABRA1 (0.41) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL25328775 0.78 GABRA1 (0.46) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL25329716 0.78 LTA4H (0.46) GABRA1GABRB2CYP2C9LTA4H
SCHEMBL13376185 0.77 KDM4E (0.41) LTA4HMAOAESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442459-B2 Solid electrolyte, membrane and electrode assembly, and fuel cell FUJIFILM CORPORATION (JP) 2008-10-28 US disclosed
US-6114487-A COATING AGENT, MOLDING MATERIAL, IMPROVED MOLD RELEASE DOW CORNING TORAY SILICONE CO., LTD. (JP) 2000-09-05 US disclosed