Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11392378 | 0.79 | TDP1 (0.38) | KMT2ACA12CA14XBP1TDP1 | |
| SCHEMBL526638 | 0.72 | NOS1 (0.40) | LMNAKMT2ACA12CA14CA1 | |
| SCHEMBL108717 | 0.72 | DGAT1 (0.39) | LMNAKMT2ACA12CA14CA1 | |
| SCHEMBL14593925 | 0.72 | DGAT1 (0.39) | LMNAKMT2ACA12CA14CA1 | |
| SCHEMBL1332536 | 0.70 | TP53 (0.38) | LMNAKMT2ACA12CA14CA1 | |
| SCHEMBL1953733 | 0.70 | TP53 (0.38) | LMNAKMT2ACA12CA14CA1 | |
| SCHEMBL305050 | 0.70 | TP53 (0.38) | LMNAKMT2ACA12CA14CA1 | |
| SCHEMBL8651672 | 0.70 | CA12 (0.37) | LMNAKMT2ACA12CA14CA1 | |
| Hydrogen Peroxide SCHEMBL22069989 | 0.70 | CA12 (0.37) | LMNAKMT2ACA12CA14CA1 | |
| SCHEMBL2962998 | 0.70 | CA14 (0.41) | LMNAKMT2ACA12CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651200-B1 | GALLOYLPEPTIDES | ASTELLAS PHARMA INC (JP) | 2008-12-24 | — | — | EP | disclosed |
| US-7273951-B2 | Polyhydroxy phenols and their use in binding p-selectin | ASTELLAS PHARMA INC. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20060276545-A1 | Polyhydroxy phenols and their use in binding p-selectin | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1651200-A1 | POLYHYDROXY PHENOLS AND THEIR USE IN BINDNG P-SELECTIN | Astellas Pharma Inc. (JP) | 2006-05-03 | — | — | EP | disclosed |
| WO-2004105740-A1 | POLYHYDROXY PHENOLS AND THEIR USE IN BINDNG P-SELECTIN | ASTELLAS PHARMA INC. (JP) | 2004-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276545-A1 | Polyhydroxy phenols and their use in binding p-selectin | SELP, SELPLG, SELE | LMNA 2763/4885KMT2A 3733/4885CA12 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.