Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 8/20 | 0.59 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479886 | 0.81 | SLC9A1 (0.65) | SLC9A1GRM2MAPTRAB9ANPC1 | |
| SCHEMBL2488643 | 0.81 | SLC9A1 (0.65) | SLC9A1GRM2MAPTRAB9ANPC1 | |
| SCHEMBL12001037 | 0.81 | SLC9A1 (0.59) | SLC9A1GRM2MAPTRAB9ANPC1 | |
| SCHEMBL822764 | 0.79 | SLC9A1 (0.56) | SLC9A1GRM2MAPTRAB9ANPC1 | |
| SCHEMBL3463660 | 0.79 | SLC9A1 (0.57) | SLC9A1GRM2MAPTRAB9ANPC1 | |
| SCHEMBL251561 | 0.79 | SLC9A1 (0.66) | SLC9A1GRM2MAPTRAB9ANPC1 | |
| SCHEMBL31234269 | 0.78 | SLC9A1 (0.70) | SLC9A1GRM2MAPTRAB9ANPC1 | |
| SCHEMBL1774497 | 0.78 | SLC9A1 (0.70) | SLC9A1GRM2MAPTRAB9ANPC1 | |
| SCHEMBL19586677 | 0.77 | SLC9A1 (0.59) | SLC9A1GRM2MAPTRAB9ANPC1 | |
| SCHEMBL14074964 | 0.77 | SLC9A1 (0.54) | SLC9A1GRM2MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419962-B2 | 3,6-bicyclolides | ENANTA PHARMACEUTICALS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| CN-101107000-A | 3,6-bicyclolides | ENANTA PHARM INC (US) | 2008-01-16 | — | — | CN | disclosed |
| US-20060142214-A1 | 3,6-bicyclolides | ENANTA PHARMACEUTICALS, INC. | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142214-A1 | 3,6-bicyclolides | ABCB11, CYP2B6, CYP3A7 | SLC9A1 2920/4885GRM2 4794/4885MAPT 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.