SCHEMBL501797

SCHEMBL501797

CCCCCCCCCCCCCCCCCCCCCC([O])=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.65
CES1 P23141 4/20 0.65
GPR84 Q9NQS5 7/20 0.62
PPARG P37231 7/20 0.62
PPARD Q03181 7/20 0.62
PPARA Q07869 7/20 0.62
HDAC11 Q96DB2 5/20 0.62
TSHR P16473 5/20 0.62
PTPN1 P18031 3/20 0.62
ALDH1A1 P00352 3/20 0.62
TLR2 O60603 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
FABP4 P15090 2/20 0.62
SLC22A6 Q4U2R8 1/20 0.62
SLC22A8 Q8TCC7 1/20 0.62
MEN1 O00255 1/20 0.62
ESR1 P03372 1/20 0.62
ALOX15 P16050 1/20 0.62
PDE4A P27815 1/20 0.62
KMT2A Q03164 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79563 1.00 CES2 (0.65) CES2CES1GPR84PPARGPPARD
SCHEMBL56011 1.00 CES2 (0.65) CES2CES1GPR84PPARGPPARD
SCHEMBL155222 1.00
SCHEMBL160220 1.00 CES2 (0.65) CES2CES1GPR84PPARGPPARD
SCHEMBL4141832 1.00 CES2 (0.65) CES2CES1GPR84PPARGPPARD
SCHEMBL54806 1.00 CES2 (0.65) CES2CES1GPR84PPARGPPARD
SCHEMBL421576 1.00 CES2 (0.65) CES2CES1GPR84PPARGPPARD
SCHEMBL41461 1.00 CES2 (0.65) CES2CES1GPR84PPARGPPARD
SCHEMBL276881 1.00 CES2 (0.65) CES2CES1GPR84PPARGPPARD
SCHEMBL205397 1.00 CES2 (0.65) CES2CES1GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829527-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-09-05 EP claimed
EP-1829528-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-09-05 EP claimed
EP-1815846-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-08-08 EP claimed
EP-1815847-A2 Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2007-08-08 EP claimed
EP-1551370-A1 AGGREGATE WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN IDEA AG (DE) 2005-07-13 EP claimed
US-6787525-B1 METHOD OF TREATING HIV INFECTIONS AND/OR CANCER DISEASES SCHOTT HERBERT (DE) 2004-09-07 US claimed
US-20040105881-A1 Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin IDEA AG (DE) 2004-06-03 US claimed
WO-2004032900-A1 AGGREGATE WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN IDEA AG (DE) 2004-04-22 WO claimed
EP-1135401-B1 GLYCERYL NUCLEOTIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE SCHOTT HERBERT (DE) 2003-06-18 EP claimed
EP-1135401-A1 GLYCERYL NUCLEOTIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE SCHOTT, Herbert (DE) 2001-09-26 EP claimed
WO-2000034298-A1 GLYCERYL NUCLEOTIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE SCHOTT HERBERT (DE) 2000-06-15 WO claimed
US-5191071-A Nonionic surfactants NOVO NORDISK A/S (DK) 1993-03-02 US claimed
CN-114449994-A Cosmetic or dermatological composition for cleansing and/or removing cosmetics, comprising succinic acid, for preventing, reducing or eliminating skin defects, treating skin diseases and preventing, treating and combating excessive seborrhoeic disorders of the scalp 罗盖特公司 2022-05-06 CN disclosed
CN-107982082-B Transparent shampoo composition 日油株式会社 2021-12-31 CN disclosed
CN-107811880-B Transparent shampoo composition 日油株式会社 2021-12-31 CN disclosed
EP-2013240-B1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO LTD (JP) 2017-05-31 EP disclosed
EP-0056992-A1 Phosphorylated derivatives, pharmaceutical compositions containing such derivatives, and their use CIBA-GEIGY AG (CH) 1982-08-04 EP disclosed
EP-0034347-A2 Derivatives of aldohexoses, intermediates, process for their production, preparations containing such compositions and their use CIBA-GEIGY AG (CH) 1981-08-26 EP disclosed
EP-0026746-A1 Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production CIBA-GEIGY AG (CH) 1981-04-08 EP disclosed
US-3936462-A CNS DEPRESSANT, ANALGESIC STERLING DRUG INC. (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040105881-A1 Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin CUTA, ABCG2, PIGS CES2 935/4885CES1 2798/4885GPR84 2355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.