SCHEMBL501946

SCHEMBL501946

C=CC(=O)OCCC[SiH](C)O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.61
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 2/20 0.61
HPGD P15428 1/20 0.60
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.42
ATM Q13315 1/20 0.39
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HCAR2 Q8TDS4 3/20 0.35
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1585542 0.86 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8326378 0.85 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21694054 0.84 TSHR (0.65) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7525910 0.81 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1741816 0.81 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL18381172 0.81 TSHR (0.67) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL19275157 0.81 TSHR (0.44) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25262634 0.80 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16901529 0.80 TSHR (0.44) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17483940 0.80 TSHR (0.44) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4563514-A Curable polysilarylene-polysiloxane copolymers GENERAL ELECTRIC COMPANY (US) 1986-01-07 US claimed
US-12630654-B2 Emulsion particle-containing aqueous dispersion NIPPON SHOKUBAI CO., LTD. (JP) 2026-05-19 US disclosed
EP-4726008-A1 AGENT FOR IMPARTING HYDROPHILICITY-SUSTAINING EFFECT AND/OR WATER SLIDING PROPERTIES Nippon Shokubai Co., Ltd. (JP) 2026-04-15 EP disclosed
US-12590215-B2 Ink for ink-jet textile printing, method for producing printed matter using said ink, and article with adhered image NIPPON SHOKUBAI CO., LTD. (JP) 2026-03-31 US disclosed
US-12503614-B2 Resin emulsion for water-based ink NIPPON SHOKUBAI CO., LTD. (JP) 2025-12-23 US disclosed
US-12473456-B2 Aqueous dispersion, production method therefor, coating composition, and coating film NIPPON SHOKUBAI CO., LTD. (JP) 2025-11-18 US disclosed
CN-119487255-A Fiber-treating agent for rubber reinforcement, set of fiber-treating agents for rubber reinforcement, method for producing fiber for rubber reinforcement, and rubber product 明成化学工业株式会社 2025-02-18 CN disclosed
CN-114945638-B Resin emulsion for water-based ink 株式会社日本触媒 2025-01-07 CN disclosed
WO-2024252703-A1 AGENT FOR IMPARTING HYDROPHILICITY-SUSTAINING EFFECT AND/OR WATER SLIDING PROPERTIES 株式会社日本触媒 2024-12-12 WO disclosed
US-20240294787-A1 INK FOR INK-JET TEXTILE PRINTING, METHOD FOR PRODUCING PRINTED MATTER USING SAID INK, AND ARTICLE WITH ADHERED IMAGE NIPPON SHOKUBAI CO., LTD. (JP) 2024-09-05 US disclosed
WO-2011049919-A1 HYDROPHILICALLY-MODIFIED SILICONE COMPOSITIONS DOW CORNING CORPORATION (US) 2011-04-28 WO disclosed
US-20110046306-A1 THERMOPLASTIC POLYURETHANE COMPOSITION BASF SE (DE) 2011-02-24 US disclosed
EP-2271712-A1 THERMOPLASTIC POLYURETHANE COMPOSITION BASF SE (DE) 2011-01-12 EP disclosed
WO-2010093526-A1 HEALTH MANAGEMENT CUFF CHARLES CHELSEA (US) 2010-08-19 WO disclosed
WO-2009132947-A1 THERMOPLASTIC POLYURETHANE COMPOSITION BASF SE (DE) 2009-11-05 WO disclosed
US-20090162816-A1 HEALTH MANAGEMENT CUFF CHARLES CHELSEA 2009-06-25 US disclosed
US-5914420-A UNSTRAINED POLYMERIZABLE CYCLOSILOXANES HAVING A SUBSTITUENT THAT CONTAINS A PERFLUORINATED ORGANIC MOIETY PCR, INC. (US) 1999-06-22 US disclosed
US-5892086-A Perfluorinated ether organo substituted cyclosiloxanes and copolymers prepared from these cyclosiloxanes PCR, INC. (US) 1999-04-06 US disclosed
US-5494979-A RADIATION CURABLE ACRYLATED SILICON POLYMERS AS RELEASE AGENTS FOR PROTECTIVE BACKINGS OF MATERIALS COATED WITH PRESSURE SENSITIVE ADHESIVES TH. GOLDSCHMIDT AG (DE) 1996-02-27 US disclosed
US-4563514-A Curable polysilarylene-polysiloxane copolymers GENERAL ELECTRIC COMPANY (US) 1986-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630654-B2 Emulsion particle-containing aqueous dispersion CLTB, CLTA, APOB TSHR 3515/4885ALDH1A1 559/4885CYP3A4 1827/4885
US-12590215-B2 Ink for ink-jet textile printing, method for producing printed matter using said ink, and article with adhered image PSD, EPHA7, EED TSHR 4240/4885ALDH1A1 324/4885CYP3A4 1325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.