Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585542 | 0.86 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL501946 | 0.85 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL1741816 | 0.81 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL7525910 | 0.81 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL18381172 | 0.81 | TSHR (0.67) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25262634 | 0.80 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL21694054 | 0.80 | TSHR (0.65) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL139742 | 0.79 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL4849695 | 0.79 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL3338971 | 0.79 | TSHR (0.58) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914420-A | UNSTRAINED POLYMERIZABLE CYCLOSILOXANES HAVING A SUBSTITUENT THAT CONTAINS A PERFLUORINATED ORGANIC MOIETY | PCR, INC. (US) | 1999-06-22 | — | — | US | disclosed |
| US-5892086-A | Perfluorinated ether organo substituted cyclosiloxanes and copolymers prepared from these cyclosiloxanes | PCR, INC. (US) | 1999-04-06 | — | — | US | disclosed |
| US-5494979-A | RADIATION CURABLE ACRYLATED SILICON POLYMERS AS RELEASE AGENTS FOR PROTECTIVE BACKINGS OF MATERIALS COATED WITH PRESSURE SENSITIVE ADHESIVES | TH. GOLDSCHMIDT AG (DE) | 1996-02-27 | — | — | US | disclosed |