SCHEMBL7525910

SCHEMBL7525910

C=CC(=O)OCCC[SiH](C)OC

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.57
ALDH1A1 P00352 4/20 0.57
CYP3A4 P08684 2/20 0.57
HPGD P15428 1/20 0.56
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 2/20 0.40
ATM Q13315 1/20 0.37
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1741816 0.86 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25262634 0.84 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL139742 0.84 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1585542 0.83 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL4849695 0.83 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3338971 0.83 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28074744 0.82 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8326378 0.81 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL501946 0.81 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28174480 0.81 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449413-B1 Polymers ICI PLC (GB) 1995-12-20 EP claimed
US-5274064-A An addition polymer having a \"hub\" of a tri-to octathiol; crosslinking IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-28 US claimed
EP-0449413-A1 Polymers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-02 EP claimed
CN-116661191-A Liquid crystal display device having a light shielding layer 三星SDI株式会社 2023-08-29 CN disclosed
US-20220307629-A1 Structure of Composite Flexible Pipeline for Crude Oil and Natural Gas Transportation and Laying Method Therefor KURARAY CO., LTD. (JP) 2022-09-29 US disclosed
CN-106574152-A Adhesive film and display member using same 三星SDI株式会社 2017-04-19 CN disclosed
CN-102282227-B Coating composition 3M INNOVATIVE PROPERTIES CO. (US) 2014-10-29 CN disclosed
CN-102282227-A Coating composition 2011-12-14 CN disclosed
US-20020016269-A1 Particle perfume delivery system THE PROCTER & GAMBLE CO. 2002-02-07 US disclosed
WO-2002004586-A1 A PARTICLE PERFUME DELIVERY SYSTEM THE PROCTER & GAMBLE COMPANY (US) 2002-01-17 WO disclosed
WO-2000068275-A1 NON-SYMMETRICAL FREE RADICAL INITIATORS AND PROCESS FOR USE THEREWITH THE PROCTER & GAMBLE COMPANY (US) 2000-11-16 WO disclosed
EP-0449413-B1 Polymers ICI PLC (GB) 1995-12-20 EP disclosed
US-5274064-A An addition polymer having a \"hub\" of a tri-to octathiol; crosslinking IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-28 US disclosed
EP-0449413-A1 Polymers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-02 EP disclosed