Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 6/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ACP1 | P24666 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699152 | 0.71 | LMNA (0.39) | KMT2AHTTNPSR1HPGDSLMNA | |
| SCHEMBL3699149 | 0.71 | LMNA (0.39) | KMT2AHTTNPSR1HPGDSLMNA | |
| SCHEMBL4569348 | 0.70 | SYK (0.36) | KMT2AHTTLMNAKDM4ESMARCA2 | |
| SCHEMBL5019523 | 0.68 | AVPR1B (0.35) | HTTNPSR1LMNASIGMAR1 | |
| SCHEMBL16412325 | 0.64 | AVPR1B (0.39) | CNR1CNR2 | |
| SCHEMBL4569341 | 0.63 | PIK3CD (0.45) | KMT2AMAPTHTTLMNAKDM4E | |
| SCHEMBL15306521 | 0.63 | AVPR1B (0.39) | CNR1CNR2 | |
| SCHEMBL15336733 | 0.62 | PIK3R2 (0.38) | — | |
| SCHEMBL3696676 | 0.62 | PIK3CD (0.48) | — | |
| SCHEMBL4535138 | 0.61 | SIGMAR1 (0.41) | CNR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064973-A2 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |