SCHEMBL5019539

SCHEMBL5019539

CCOc1ccc(C)c2c1B(O)OC2CN

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LARS1 Q9P2J5 4/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL462459 0.99 LARS1 (0.75) LARS1
SCHEMBL18023406 0.87
SCHEMBL18023441 0.87
SCHEMBL469428 0.85 LARS1 (0.73) LARS1
SCHEMBL469460 0.85 LARS1 (1.00) LARS1
SCHEMBL454459 0.85 LARS1 (1.00) LARS1
SCHEMBL453500 0.85 LARS1 (1.00) LARS1
SCHEMBL469474 0.85 LARS1 (0.73) LARS1
SCHEMBL469397 0.85 LARS1 (1.00) LARS1
SCHEMBL453354 0.85 LARS1 (0.73) LARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11008345-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2021-05-18 US disclosed
US-11008345-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2021-05-18 US disclosed
CN-108610356-B Benzoxaborole derivatives for the treatment of bacterial infections 阿纳科制药公司 2021-02-26 CN disclosed
US-20190345173-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, LLC 2019-11-14 US disclosed
US-20190345173-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, LLC 2019-11-14 US disclosed
US-9889146-B2 Benzoxaborole compounds and uses thereof ANACOR PHARMACEUTICALS, INC. (US) 2018-02-13 US disclosed
US-9889146-B2 Benzoxaborole compounds and uses thereof ANACOR PHARMACEUTICALS, INC. (US) 2018-02-13 US disclosed
US-20170355719-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2017-12-14 US disclosed
US-20170355719-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2017-12-14 US disclosed
US-20170355719-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2017-12-14 US disclosed
US-20170071961-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF ANACOR PHARMACEUTICALS, LLC 2017-03-16 US disclosed
US-20170071961-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF ANACOR PHARMACEUTICALS, LLC 2017-03-16 US disclosed
US-20150080342-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE LLC 2015-03-19 US disclosed
US-20150080342-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE LLC 2015-03-19 US disclosed
US-20140315860-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2014-10-23 US disclosed
US-20140315860-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2014-10-23 US disclosed
WO-2013154759-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF ANACOR PHARMACEUTICALS, INC. (US) 2013-10-17 WO disclosed
US-20120115813-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2012-05-10 US disclosed
US-20120115813-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2012-05-10 US disclosed
WO-2012033858-A2 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170071961-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF NSUN3, BCAT2, FARSB LARS1 57/4885
US-11008345-B2 Boron-containing small molecules BCL6B, BTD, BROX LARS1 2597/4885
US-20150080342-A1 BENZOXABOROLE COMPOUNDS AND USES THEREOF NSUN3, BCAT2, FARSB LARS1 57/4885
US-20120115813-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BTD, BROX LARS1 2597/4885
US-20170355719-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BTD, BROX LARS1 2597/4885
US-20190345173-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BTD, BROX LARS1 2597/4885
US-20140315860-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BTD, BROX LARS1 2597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.