Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019754 | 0.88 | GRM5 (0.40) | KMT2AMEN1TP53THRB | |
| SCHEMBL5019740 | 0.85 | GAA (0.42) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1781817 | 0.85 | KMT2A (0.50) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL986998 | 0.82 | STIM1 (0.42) | KMT2A | |
| SCHEMBL5019638 | 0.81 | KMT2A (0.41) | LCLAT1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL5019609 | 0.81 | AVPR2 (0.42) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL5019637 | 0.81 | KMT2A (0.41) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL4561040 | 0.81 | KMT2A (0.35) | MAPTKMT2ANPC1RAB9ATSHR | |
| SCHEMBL987243 | 0.80 | IL2 (0.43) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL5019742 | 0.80 | MAPT (0.39) | MAPTKMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064808-A1 | TETRAZOLYL - TETRAHYDROPYRIDINE COMPOUNDS FOR INFLAMMATION AND IMMUNE - RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2012-05-18 | — | — | WO | disclosed |