Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019587 | 0.88 | LCLAT1 (0.40) | THRBMEN1KMT2ATP53 | |
| SCHEMBL1781784 | 0.88 | SMO (0.44) | MEN1KMT2ALMNAWDR5 | |
| SCHEMBL5019637 | 0.85 | KMT2A (0.41) | NR3C1MEN1KMT2ATP53WDR5 | |
| SCHEMBL5019716 | 0.84 | RAB9A (0.47) | MEN1KMT2ALMNATP53 | |
| SCHEMBL1781817 | 0.84 | KMT2A (0.50) | MEN1KMT2ALMNATP53 | |
| SCHEMBL1781495 | 0.84 | RAB9A (0.38) | NR3C1MEN1KMT2ATP53PTPN11 | |
| SCHEMBL5019718 | 0.84 | THRB (0.36) | THRBLMNATP53PPARGIKBKB | |
| SCHEMBL5019717 | 0.83 | CRACR2A (0.39) | — | |
| SCHEMBL5019638 | 0.83 | KMT2A (0.41) | KMT2ALMNATP53AVPR2WDR5 | |
| SCHEMBL5019609 | 0.83 | AVPR2 (0.42) | MEN1KMT2ALMNATP53AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064808-A1 | TETRAZOLYL - TETRAHYDROPYRIDINE COMPOUNDS FOR INFLAMMATION AND IMMUNE - RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2012-05-18 | — | — | WO | disclosed |