Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019601 | 0.94 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL5019723 | 0.91 | KMT2A (0.40) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL5019626 | 0.90 | KDM4E (0.37) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL15356912 | 0.86 | KMT2A (0.31) | KMT2A | |
| SCHEMBL5019621 | 0.85 | KDM4E (0.38) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL5019751 | 0.84 | RAB9A (0.38) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL5019577 | 0.81 | KDM4E (0.38) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL5019638 | 0.80 | KMT2A (0.41) | SMN1; SMN2KMT2APOLBALDH1A1AURKA | |
| SCHEMBL5019600 | 0.78 | JAK1 (0.37) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL15356919 | 0.77 | KMT2A (0.32) | KDM4EKMT2AMAPTTP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064808-A1 | TETRAZOLYL - TETRAHYDROPYRIDINE COMPOUNDS FOR INFLAMMATION AND IMMUNE - RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2012-05-18 | — | — | WO | disclosed |