Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019765 | 0.90 | CSNK1D (0.37) | SMYD3HPGDMAPTSMN1; SMN2RAB9A | |
| SCHEMBL5019624 | 0.87 | MAPT (0.40) | MAPTSMN1; SMN2ACKR3POLBMTOR | |
| SCHEMBL5019710 | 0.86 | MAPT (0.34) | HPGDALOX15HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL5019578 | 0.85 | MAPT (0.36) | MAPTSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL5019719 | 0.85 | MAPT (0.33) | HPGDALOX15HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL5019602 | 0.83 | SMYD3 (0.36) | SMYD3HPGDMAPTSMN1; SMN2ACKR3 | |
| SCHEMBL5019605 | 0.82 | L3MBTL1 (0.35) | HPGDMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5019621 | 0.82 | KDM4E (0.38) | HPGDHSD17B10MAPTSMN1; SMN2RAB9A | |
| SCHEMBL5019613 | 0.81 | CSNK1D (0.38) | SMYD3HPGDMAPTSMN1; SMN2ACKR3 | |
| SCHEMBL1781495 | 0.79 | RAB9A (0.38) | HPGDMAPTRAB9ANPC1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064808-A1 | TETRAZOLYL - TETRAHYDROPYRIDINE COMPOUNDS FOR INFLAMMATION AND IMMUNE - RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2012-05-18 | — | — | WO | disclosed |