Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CAD | P27708 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020127 | 0.88 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCADGAA | |
| SCHEMBL4984189 | 0.83 | L3MBTL1 (0.46) | L3MBTL1KMT2APOLBCADGAA | |
| SCHEMBL5058848 | 0.83 | L3MBTL1 (0.61) | L3MBTL1KMT2APOLBCADGAA | |
| SCHEMBL15158367 | 0.81 | PSMB5 (0.45) | KMT2APSMB5POLBMEN1KDM4E | |
| SCHEMBL10530552 | 0.80 | PSMB5 (0.46) | L3MBTL1KMT2APSMB5POLBCAD | |
| SCHEMBL4984212 | 0.79 | L3MBTL1 (0.43) | L3MBTL1KMT2APOLBCADGAA | |
| SCHEMBL29543223 | 0.78 | L3MBTL1 (0.47) | L3MBTL1KMT2APOLBCADGAA | |
| SCHEMBL2140677 | 0.78 | KMT2A (0.53) | L3MBTL1KMT2APOLBCADGAA | |
| SCHEMBL4537405 | 0.78 | METAP2 (0.43) | L3MBTL1KMT2APSMB5POLBCAD | |
| SCHEMBL7620116 | 0.78 | METAP2 (0.43) | L3MBTL1KMT2APSMB5POLBCAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065102-A2 | S-T-BUTYL PROTECTED CYSTEINE DI-PEPTIDE ANALOGS AND RELATED COMPOUNDS | PROMENTIS PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |