SCHEMBL10530552

SCHEMBL10530552

CCOC(=O)C(NC(=O)CNC(=O)CC)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 2/20 0.46
GAA P10253 2/20 0.41
KMT2A Q03164 3/20 0.38
MEN1 O00255 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
POLB P06746 1/20 0.36
MGAM O43451 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
SOAT1 P35610 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
CYP2C9 P11712 1/20 0.34
CAD P27708 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10530534 0.86 GAA (0.39) PSMB5GAAKMT2AL3MBTL1POLB
SCHEMBL16577950 0.86 GAA (0.39) PSMB5GAAKMT2AMEN1L3MBTL1
SCHEMBL10533433 0.84 CAD (0.44) PSMB5GAAKMT2AL3MBTL1POLB
SCHEMBL16577987 0.83 GAA (0.44) PSMB5GAAKMT2AL3MBTL1POLB
SCHEMBL12160526 0.82 EGLN1 (0.38) PSMB5GAAKMT2AL3MBTL1POLB
SCHEMBL12160523 0.80 GAA (0.38) PSMB5GAAKMT2AL3MBTL1POLB
SCHEMBL17987547 0.80 ALDH1A1 (0.44) GAAKMT2AMEN1CYP2C9CA1
SCHEMBL10493682 0.80 L3MBTL1 (0.42) GAAKMT2AL3MBTL1POLBMGAM
SCHEMBL5020129 0.80 L3MBTL1 (0.44) PSMB5GAAKMT2AMEN1L3MBTL1
SCHEMBL13253167 0.78 ALDH1A1 (0.45) GAAKMT2AMEN1CYP2C9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4886894-A ANTITUMOR AGENTS Tanabe Seivaku Co., Ltd. (JP) 1989-12-12 US disclosed
CN-88101195-A novel organic platinum complex and preparation method thereof 1988-09-28 CN disclosed
EP-0281412-A2 Novel organic platinum complex pharmaceutical compositions containing same and a process for the preparation thereof Tanabe Seiyaku Co., Ltd. (JP) 1988-09-07 EP disclosed