Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP7 | P09237 | 2/20 | 0.38 |
| ▸ | MMP10 | P09238 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.36 |
| ▸ | NMT1 | P30419 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020184 | 0.91 | BRD4 (0.43) | MMP1MMP2MMP3MMP7MMP10 | |
| SCHEMBL5020143 | 0.90 | MMP8 (0.39) | MMP1MMP2MMP3MMP7MMP10 | |
| SCHEMBL8777128 | 0.76 | GAA (0.45) | GAAALOX15LMNAMMP1MMP2 | |
| SCHEMBL5020142 | 0.68 | MMP2 (0.43) | MMP1MMP2MMP3MMP7MMP10 | |
| SCHEMBL8777638 | 0.68 | MMP2 (0.40) | MMP1MMP2MMP3MMP7MMP10 | |
| SCHEMBL4906501 | 0.68 | PADI3 (0.38) | GAAMMP1MMP2MMP3MMP7 | |
| SCHEMBL6478104 | 0.67 | TSHR (0.50) | GAAHDAC1TSHRCYP2C19CYP2D6 | |
| SCHEMBL8777624 | 0.67 | BRD4 (0.41) | MMP1MMP2MMP3MMP7MMP10 | |
| SCHEMBL5020145 | 0.67 | NMT1 (0.37) | MMP1MMP2MMP3MMP7MMP10 | |
| SCHEMBL7788580 | 0.66 | TSHR (0.67) | GAAALOX15LMNAHDAC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064943-A2 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |