SCHEMBL5020245

SCHEMBL5020245

COc1ccc(C(=O)c2ccc(Oc3ccc(-c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
RAB9A P51151 3/20 0.56
RXFP1 Q9HBX9 2/20 0.56
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
MAPT P10636 1/20 0.56
MAPK1 P28482 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
PARP10 Q53GL7 1/20 0.56
HPGD P15428 1/20 0.56
ALDH1A1 P00352 3/20 0.55
MMP13 P45452 1/20 0.53
NPC1 O15118 2/20 0.53
GAA P10253 2/20 0.52
KDM4E B2RXH2 1/20 0.52
GLA P06280 1/20 0.52
ACHE P22303 1/20 0.52
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
CES2 O00748 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18656382 1.00 LMNA (0.56) LMNARAB9ARXFP1KMT2AMEN1
SCHEMBL13910601 1.00 LMNA (0.56) LMNARAB9ARXFP1KMT2AMEN1
SCHEMBL757809 1.00 LMNA (0.56) LMNARAB9ARXFP1KMT2AMEN1
SCHEMBL19353603 1.00 LMNA (0.56) LMNARAB9ARXFP1KMT2AMEN1
SCHEMBL14407936 1.00 LMNA (0.56) LMNARAB9ARXFP1KMT2AMEN1
SCHEMBL17589220 1.00 LMNA (0.56) LMNARAB9ARXFP1KMT2AMEN1
SCHEMBL13026420 1.00 LMNA (0.56) LMNARAB9ARXFP1KMT2AMEN1
SCHEMBL21935134 1.00 LMNA (0.56) LMNARAB9ARXFP1KMT2AMEN1
SCHEMBL22365124 1.00 LMNA (0.56) LMNARAB9ARXFP1KMT2AMEN1
SCHEMBL10093720 1.00 LMNA (0.56) LMNARAB9ARXFP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149804-A1 LUBRICANT COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2024-07-18 WO disclosed
US-20230374304-A1 THERMOPLASTIC POLYMER COMPOSITION SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-11-23 US disclosed
EP-3230986-B1 POLY(ARYL ETHER) COMPOSITIONS FOR POLYMER-METAL JUNCTIONS AND POLYMER-METAL JUNCTIONS AND CORRESPONDING FABRICATION METHODS SOLVAY SPECIALTY POLYMERS USA (US) 2023-11-22 EP disclosed
US-20230331979-A1 FIBER REINFORCED THERMOPLASTIC MATRIX COMPOSITE MATERIAL SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-10-19 US disclosed
WO-2023169851-A1 THERMOPLASTIC COMPOSITES MATERIALS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-09-14 WO disclosed
US-20230287176-A1 BLEND OF POLYARYLETHER KETONE COPOLYMER SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-09-14 US disclosed
US-20230287176-A1 BLEND OF POLYARYLETHER KETONE COPOLYMER SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-09-14 US disclosed
US-20230287602-A1 PROCESS FOR PREPARING A CONTINUOUS FIBER FILAMENT, CONTINUOUS FIBER FILAMENT AND USE THEREOF SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-09-14 US disclosed
US-20230287602-A1 PROCESS FOR PREPARING A CONTINUOUS FIBER FILAMENT, CONTINUOUS FIBER FILAMENT AND USE THEREOF SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-09-14 US disclosed
US-20230250230-A1 REINFORCED PAEK COMPOSITIONS COMPRISING RECYLCED CARBON FIBERS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-08-10 US disclosed
US-20110213095-A1 Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-09-01 US disclosed
US-20110213095-A1 Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-09-01 US disclosed
US-20110213115-A1 Process for preparing a poly(aryl ether ketone) using a high purity 4,4'-difluorobenzophenone SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-09-01 US disclosed
US-20110201775-A1 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-08-18 US disclosed
US-20110201775-A1 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-08-18 US disclosed
WO-2010046484-A1 METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S IN THE PRESENCE OF SODIUM CARBONATE SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-04-29 WO disclosed
WO-2010046483-A1 IMPROVED PROCESS FOR PREPARING A POLY(ARYL ETHER KETONE) USING A HIGH PURITY 4,4'-DIFLUOROBENZOPHENONE SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-04-29 WO disclosed
WO-2010046482-A1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-04-29 WO disclosed
WO-2010046487-A1 IMPROVED METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S AND IMPROVED METHOD FOR PROVIDING A SODIUM CARBONATE SUITABLE FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-04-29 WO disclosed
US-20090274943-A1 CROSSLINKED POLYMER ELECTROLYTE AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201775-A1 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) DHPS, PKM, PCBP1 LMNA 1322/4885RAB9A 4029/4885RXFP1 4813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.