SCHEMBL219176

SCHEMBL219176

[C](Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
TSHR P16473 3/20 0.53
TRPA1 O75762 2/20 0.53
CALM1 P0DP23 1/20 0.50
LOXL2 Q9Y4K0 2/20 0.45
IDO1 P14902 2/20 0.45
TP53 P04637 1/20 0.45
HPGD P15428 2/20 0.43
MAOB P27338 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
CASP1 P29466 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 2/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
CYP1A1 P04798 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4218700 0.83 TP53 (0.50) ALDH1A1TSHRTRPA1CALM1LOXL2
SCHEMBL6226882 0.81 ALDH1A1 (0.46) ALDH1A1TSHRTRPA1LOXL2HPGD
SCHEMBL3888886 0.80 CALM1 (0.50) ALDH1A1TSHRTRPA1CALM1LOXL2
SCHEMBL4228707 0.79 TP53 (0.46) ALDH1A1TSHRTRPA1CALM1IDO1
SCHEMBL7056254 0.77 SMN1; SMN2 (0.39) ALDH1A1TSHRTRPA1CALM1LOXL2
SCHEMBL502029 0.75 KCNH2 (0.46) TP53SMN1; SMN2
SCHEMBL269027 0.75
SCHEMBL398749 0.75
SCHEMBL10361972 0.75
SCHEMBL97491 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3191533-B1 POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF SIRRUS INC (US) 2020-11-04 EP claimed
US-10618987-B2 Modified catalyst supports TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2020-04-14 US claimed
US-20090098410-A1 Trimethine Dimer Compound and Optical Recording Medium Using the Same MITSUI CHEMICALS, INC. (JP) 2009-04-16 US claimed
EP-1900779-A1 TRIMETHINE DIMER COMPOUND AND OPTICAL RECORDING MEDIUM USING SAME Mitsui Chemicals, Inc. (JP) 2008-03-19 EP claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP claimed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US claimed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO claimed
CN-119707614-A Preparation method of bibenzyl compound 中国科学院大连化学物理研究所 2025-03-28 CN disclosed
CN-119707614-A Preparation method of bibenzyl compound 中国科学院大连化学物理研究所 2025-03-28 CN disclosed
US-20240199586-A1 COMPOUND OR TAUTOMER THEREOF, COMPOSITION, LAMINATE, OPTICAL FILM, IMAGE FORMING MATERIAL, AND METHOD FOR PRODUCING COMPOUND OR TAUTOMER THEREOF FUJIFILM CORPORATION (JP) 2024-06-20 US disclosed
US-20240191067-A1 ETHYLENE-alpha-OLEFIN COPOLYMER, THERMOPLASTIC RESIN COMPOSITION, FILM, AND LAMINATE MITSUI CHEMICALS, INC. (JP) 2024-06-13 US disclosed
US-20240191011-A1 ETHYLENE-alpha-OLEFIN COPOLYMER, THERMOPLASTIC RESIN COMPOSITION, AND FILM MITSUI CHEMICALS, INC. (JP) 2024-06-13 US disclosed
US-20240191068-A1 ETHYLENE RESIN COMPOSITION AND SHAPED ARTICLE MITSUI CHEMICALS, INC. (JP) 2024-06-13 US disclosed
EP-1304334-A1 NOVEL ANTIANDROGENIC AGENT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-04-23 EP disclosed
EP-1219631-A1 ANTIANDROGEN AGENTS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2002-07-03 EP disclosed
EP-1071651-A1 METHOD FOR THE PRODUCTION OF DIBENZYL CARBONATES Bayer Aktiengesellschaft (DE) 2001-01-31 EP disclosed
WO-1999052853-A1 METHOD FOR THE PRODUCTION OF DIBENZYL CARBONATES BAYER AKTIENGESELLSCHAFT (DE) 1999-10-21 WO disclosed
EP-0892816-A1 POLYMERIZATION PROCESS FOR PRODUCING POLYOLEFIN ELASTOMER, CATION-GENERATING COCATALYST FOR ACTIVATING A METALLOCENE PROCATALYST, POLYOLEFIN ELASTOMER POSSESSING A UNIQUE COMBINATION OF PROPERTIES AND PRODUCTS MANUFACTURED THEREFROM UNIROYAL CHEMICAL COMPANY, Inc. (US) 1999-01-27 EP disclosed
WO-1997038019-A1 POLYMERIZATION PROCESS FOR PRODUCING POLYOLEFIN ELASTOMER, CATION-GENERATING COCATALYST FOR ACTIVATING A METALLOCENE PROCATALYST, POLYOLEFIN ELASTOMER POSSESSING A UNIQUE COMBINATION OF PROPERTIES AND PRODUCTS MANUFACTURED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098410-A1 Trimethine Dimer Compound and Optical Recording Medium Using the Same TXNL1, TMCO1, TFPI2 ALDH1A1 3651/4885TSHR 1535/4885TRPA1 82/4885
US-20240199586-A1 COMPOUND OR TAUTOMER THEREOF, COMPOSITION, LAMINATE, OPTICAL FILM, IMAGE FORMING MATERIAL, AND METHOD FOR PRODUCING COMPOUND OR TAUTOMER THEREOF MAPT, APP, H1-10 ALDH1A1 3339/4885TSHR 3551/4885TRPA1 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.