Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16425784 | 1.00 | LMNA (0.55) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16425789 | 1.00 | LMNA (0.55) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12300250 | 0.95 | LMNA (0.61) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14310920 | 0.95 | LMNA (0.61) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18678546 | 0.95 | LMNA (0.61) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18710528 | 0.95 | LMNA (0.61) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19480913 | 0.95 | LMNA (0.61) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11974584 | 0.93 | ALDH1A1 (0.64) | LMNAALDH1A1MAPTKMT2ARAB9A | |
| SCHEMBL760051 | 0.93 | ALDH1A1 (0.64) | LMNAALDH1A1MAPTKMT2ARAB9A | |
| SCHEMBL10486276 | 0.91 | MAPT (0.64) | LMNAALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062851-A1 | POLYMERIC BEARING ARTICLES FOR USE IN ULTRA-HIGH PRESSURE AND VELOCITY ENVIRONMENTS | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2012-05-18 | — | — | WO | disclosed |