Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110777 | 0.96 | ALDH1A1 (0.76) | ALDH1A1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL1105483 | 0.90 | ALDH1A1 (0.73) | ALDH1A1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL8716886 | 0.89 | FFAR1 (0.61) | ALDH1A1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL5020739 | 0.88 | ALDH1A1 (0.84) | ALDH1A1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL24340640 | 0.88 | MAPT (0.71) | ALDH1A1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL547835 | 0.88 | MAPT (0.71) | ALDH1A1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL5681573 | 0.88 | MAPT (0.71) | ALDH1A1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL2632727 | 0.88 | MAPT (0.71) | ALDH1A1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL8104136 | 0.88 | MAPT (0.71) | ALDH1A1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL13498521 | 0.88 | MAPT (0.71) | ALDH1A1HDAC1HDAC8HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43343-E1 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-05-01 | — | — | US | disclosed |