Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PKLR | P30613 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | FABP1 | P07148 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020619 | 0.89 | HDAC1 (1.00) | HDAC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL18753536 | 0.82 | ALDH1A1 (0.78) | HDAC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL17696037 | 0.82 | MEN1 (0.71) | HDAC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL5020747 | 0.81 | HDAC1 (0.78) | HDAC1ALDH1A1HTT | |
| SCHEMBL10192086 | 0.79 | MEN1 (0.75) | HDAC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL808364 | 0.79 | ALDH1A1 (1.00) | HDAC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL15480551 | 0.79 | MEN1 (0.73) | HDAC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL30708093 | 0.78 | ALDH1A1 (0.76) | HDAC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL2702246 | 0.78 | ALDH1A1 (0.76) | HDAC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL17210223 | 0.78 | ALDH1A1 (1.00) | HDAC1ALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43343-E1 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-05-01 | — | — | US | disclosed |