Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | FABP1 | P07148 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PKLR | P30613 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192086 | 0.86 | MEN1 (0.75) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL30708093 | 0.85 | ALDH1A1 (0.76) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL2702246 | 0.85 | ALDH1A1 (0.76) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL15713614 | 0.84 | ALDH1A1 (0.72) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL18753536 | 0.84 | ALDH1A1 (0.78) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL17696037 | 0.83 | MEN1 (0.71) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL15480551 | 0.83 | MEN1 (0.73) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL23879937 | 0.82 | MEN1 (0.70) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL22422345 | 0.82 | TP53 (1.00) | ALDH1A1GAAMEN1KMT2ATP53 | |
| SCHEMBL23879935 | 0.82 | MEN1 (0.74) | ALDH1A1GAAMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2617415-B1 | USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS | CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION (KR) | 2016-04-20 | — | — | EP | claimed |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | MSP CO., LTD. (KR) | 2015-09-10 | — | — | US | disclosed |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | MSP CO., LTD. (KR) | 2015-09-10 | — | — | US | disclosed |
| US-9068166-B2 | Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-06-30 | — | — | US | disclosed |
| US-9068166-B2 | Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-06-30 | — | — | US | disclosed |
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2013-09-12 | — | — | US | disclosed |
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2013-09-12 | — | — | US | disclosed |
| WO-2012036512-A2 | USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS | 연세대학교 산학협력단 (KR) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | COL2A1, MYADM, COL1A1 | ALDH1A1 47/4885GAA 2400/4885MEN1 3963/4885 |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | COL2A1, MYADM, COL1A1 | ALDH1A1 23/4885GAA 2243/4885MEN1 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.