Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.79 |
| ▸ | ACLY | P53396 | 15/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020630 | 0.88 | HDAC1 (1.00) | HDAC1ACLYHDAC8 | |
| SCHEMBL5020767 | 0.85 | HDAC1 (0.78) | HDAC1HDAC8 | |
| SCHEMBL15480545 | 0.78 | ACLY (0.74) | HDAC1ACLYHDAC8 | |
| SCHEMBL5020762 | 0.77 | HDAC1 (0.76) | HDAC1HDAC8 | |
| SCHEMBL21999811 | 0.77 | ACLY (1.00) | HDAC1ACLYALPL | |
| SCHEMBL94411 | 0.77 | ACLY (0.70) | HDAC1ACLYALPL | |
| SCHEMBL5020759 | 0.77 | HDAC1 (0.77) | HDAC1HDAC8 | |
| SCHEMBL21999815 | 0.74 | ACLY (1.00) | HDAC1ACLYALPL | |
| SCHEMBL28274067 | 0.74 | ALDH1A1 (0.64) | HDAC1ACLY | |
| SCHEMBL21999492 | 0.74 | ACLY (1.00) | HDAC1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43343-E1 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-05-01 | — | — | US | disclosed |