Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.78 |
| ▸ | MMP1 | P03956 | 4/20 | 0.56 |
| ▸ | MMP2 | P08253 | 4/20 | 0.56 |
| ▸ | MMP9 | P14780 | 4/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14629549 | 0.90 | HDAC1 (0.63) | HDAC1MMP1MMP2MMP9EGFR | |
| SCHEMBL5020626 | 0.88 | HDAC1 (1.00) | HDAC1TSHR | |
| SCHEMBL5047586 | 0.84 | HDAC1 (1.00) | HDAC1TSHR | |
| SCHEMBL5020747 | 0.82 | HDAC1 (0.78) | HDAC1TSHR | |
| SCHEMBL20657293 | 0.76 | HDAC1 (0.60) | HDAC1MMP1MMP2MMP9EGFR | |
| N-O-Tolylcinnamamide SCHEMBL2593754 | 0.74 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA | |
| N-O-Tolylcinnamamide SCHEMBL15902545 | 0.74 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA | |
| N-O-Tolylcinnamamide SCHEMBL29844171 | 0.74 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA | |
| N-O-Tolylcinnamamide SCHEMBL2593756 | 0.74 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL4471817 | 0.74 | KDM4E (0.57) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43343-E1 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-05-01 | — | — | US | disclosed |