Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.60 |
| ▸ | MMP1 | P03956 | 5/20 | 0.59 |
| ▸ | MMP2 | P08253 | 5/20 | 0.59 |
| ▸ | MMP9 | P14780 | 5/20 | 0.59 |
| ▸ | EGFR | P00533 | 5/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657290 | 0.88 | NAMPT (0.59) | — | |
| SCHEMBL20657342 | 0.85 | ALDH1A1 (0.54) | HDAC1MMP1MMP2MMP9EGFR | |
| SCHEMBL20657324 | 0.84 | EGFR (0.50) | HDAC1EGFRMAOBHDAC3HDAC4 | |
| SCHEMBL20657312 | 0.84 | HDAC1 (0.47) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL20657351 | 0.84 | HDAC1 (0.50) | HDAC1MMP1MMP2MMP9EGFR | |
| SCHEMBL11063104 | 0.83 | MMP1 (0.63) | HDAC1MMP1MMP2MMP9EGFR | |
| SCHEMBL11063103 | 0.83 | MMP1 (0.63) | HDAC1MMP1MMP2MMP9EGFR | |
| SCHEMBL3820006 | 0.82 | TGM2 (0.56) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL23881374 | 0.81 | HDAC1 (0.50) | HDAC1MMP1MMP2MMP9EGFR | |
| SCHEMBL20657340 | 0.81 | HDAC1 (0.45) | HDAC1MAOBHDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2023-09-07 | — | — | US | disclosed |
| US-20210309622-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2021-10-07 | — | — | US | disclosed |
| US-11052078-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-07-06 | — | — | US | disclosed |
| US-11040949-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-06-22 | — | — | US | disclosed |
| US-20200392095-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-12-17 | — | — | US | disclosed |
| US-20200261438-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-08-20 | — | — | US | disclosed |
| US-20190022038-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2019-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040949-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | TYR, ALAD, NQO1 | HDAC1 3174/4885MMP1 1317/4885MMP2 1543/4885 |
| US-20200392095-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | HDAC1 3174/4885MMP1 1317/4885MMP2 1543/4885 |
| US-11052078-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | TYR, ALAD, NQO1 | HDAC1 3174/4885MMP1 1317/4885MMP2 1543/4885 |
| US-20210309622-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | HDAC1 3174/4885MMP1 1317/4885MMP2 1543/4885 |
| US-20200261438-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | HDAC1 3174/4885MMP1 1317/4885MMP2 1543/4885 |
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | HDAC1 3174/4885MMP1 1317/4885MMP2 1543/4885 |
| US-20190022038-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | HDAC1 3174/4885MMP1 1317/4885MMP2 1543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.