Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13525403 | 0.88 | KMT2A (0.40) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL10029650 | 0.87 | MEN1 (0.36) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL12733763 | 0.87 | RAB9A (0.41) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL26845473 | 0.87 | RAB9A (0.41) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL13602010 | 0.87 | RAB9A (0.41) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL10029646 | 0.86 | MAPT (0.39) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL26845357 | 0.86 | MEN1 (0.52) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL26266082 | 0.86 | MEN1 (0.52) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL347455 | 0.85 | MAPT (0.41) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL11949226 | 0.85 | MAPT (0.41) | MEN1KMT2AMAPTHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670476-B2 | Enzyme substrate comprising a functional dye and associated technology and methods | BIOTIUM, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160237421-A9 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-20140273151-A1 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| US-8778627-B2 | Enzyme substrate comprising a functional dye and associated technology and methods | BIOTIUM, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8586325-B2 | Enzyme substrate comprising a functional dye and associated technology and methods | BIOTIUM, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20130236888-A1 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. (US) | 2013-09-12 | — | — | US | disclosed |
| US-20120115129-A1 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. (US) | 2012-05-10 | — | — | US | disclosed |
| US-8092784-B2 | Enzyme substrate comprising a functional dye and associated technology and methods | BIOTIUM, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20090148386-A1 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. | 2009-06-11 | — | — | US | disclosed |
| WO-2007100392-A2 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | BIOTIUM, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130236888-A1 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | ENGASE, GBA3, HSD17B14 | MEN1 2545/4885KMT2A 3358/4885MAPT 2600/4885 |
| US-20120115129-A1 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS | ENGASE, GBA3, HSD17B14 | MEN1 2545/4885KMT2A 3358/4885MAPT 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.