SCHEMBL502086

SCHEMBL502086

CC1(C)CCC(C)(C)c2cc(N(CC3CC3)c3ncc(C(=O)O)cn3)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RXRA P19793 18/20 1.00
RXRB P28702 17/20 1.00
RXRG P48443 17/20 1.00
PPARG P37231 1/20 0.44
NR1H3 Q13133 1/20 0.44
RARB P10826 3/20 0.44
RARG P13631 3/20 0.44
CYP26A1 O43174 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP26B1 Q9NR63 1/20 0.43
RARA P10276 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5180019 0.87 RXRA (0.76) RXRARXRBRXRGPPARGNR1H3
SCHEMBL17049104 0.86 RXRA (1.00) RXRARXRBRXRGPPARGNR1H3
SCHEMBL13368670 0.85 RXRA (0.74) RXRARXRBRXRGCYP26B1
SCHEMBL13621649 0.84 RXRA (0.73) RXRARXRBRXRGCYP26B1
SCHEMBL5180811 0.84 RXRA (0.83) RXRARXRBRXRGPPARGNR1H3
SCHEMBL17053975 0.83 RXRA (0.76) RXRARXRBRXRGPPARGNR1H3
SCHEMBL5179608 0.83 RXRA (0.76) RXRARXRBRXRGPPARGNR1H3
SCHEMBL5179870 0.80 RXRA (0.72) RXRARXRBRXRGPPARGNR1H3
SCHEMBL17053989 0.76 RXRA (1.00) RXRARXRBRXRGPPARG
SCHEMBL17049094 0.75 RXRA (0.78) RXRARXRBRXRGPPARGNR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12571046-B2 Methods of detecting and treating multiple system atrophy THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) 2026-03-10 US claimed
EP-4334436-A1 METHOD FOR INDUCING HYPERTROPHIC MUSCLE FIBERS FOR INDUSTRIAL MEAT PRODUCTION Yeda Research and Development Co. Ltd (IL) 2024-03-13 EP claimed
US-20240074473-A1 METHOD FOR INDUCING HYPERTROPHIC MUSCLE FIBERS FOR INDUSTRIAL MEAT PRODUCTION YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-03-07 US claimed
WO-2022234586-A1 METHOD FOR INDUCING HYPERTROPHIC MUSCLE FIBERS FOR INDUSTRIAL MEAT PRODUCTION YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-11-10 WO claimed
US-20090291492-A1 METHOD FOR FORMING ORGAN RESEARCH FOUNDATION ITSUU LABORATORY (JP) 2009-11-26 US claimed
US-20070161105-A1 Method of forming organ REASEARCH FOUNDATION ITSUU LABORATORY (JP) 2007-07-12 US claimed
EP-1612264-A1 ORGAN-FORMING METHOD Research Foundation Itsuu Laboratory (JP) 2006-01-04 EP claimed
US-12571046-B2 Methods of detecting and treating multiple system atrophy THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) 2026-03-10 US disclosed
US-12533309-B2 Minoxidil adjuvant therapies CARING BRANDS, INC. (US) 2026-01-27 US disclosed
US-12527729-B2 Minoxidil adjuvant therapies CARING BRANDS, INC. (US) 2026-01-20 US disclosed
US-20260015352-A1 METHYLTRANSFERASE INHIBITOR AND USE THEREOF CYTOSINLAB THERAPEUTICS CO LTD (CN) 2026-01-15 US disclosed
US-20250360128-A1 MINOXIDIL ADJUVANT THERAPIES JUPITER WELLNESS INC (US) 2025-11-27 US disclosed
US-20250346631-A1 PEPTIDE COMPOSITIONS AND METHODS OF USE ONL THERAPEUTICS INC (US) 2025-11-13 US disclosed
JP-2009215178-A NEW APPLICATION OF PYRIMIDINE-5-CARBOXYLIC ACID DERIVATIVE AS ANTIOBESTIC AGENT KOKURITSU IYAKUHIN SHOKUHIN EISEI KENKYUSHO 2009-09-24 JP disclosed
US-20070161105-A1 Method of forming organ REASEARCH FOUNDATION ITSUU LABORATORY (JP) 2007-07-12 US disclosed
EP-1180520-B1 PYRIMIDINE CARBOXYLIC ACID DERIVATIVES INST MED MOLECULAR DESIGN INC (JP) 2007-06-20 EP disclosed
EP-1612264-A1 ORGAN-FORMING METHOD Research Foundation Itsuu Laboratory (JP) 2006-01-04 EP disclosed
WO-2005099759-A1 MEDICINE FOR PREVENTION AND/OR TREATMENT OF ARTERIOSCLEROSIS INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) 2005-10-27 WO disclosed
US-6869959-B1 Heterocyclic carboxylic acid derivatives INSTITUTE OF MEDICINAL MOLECULAR DESIGN INC. (JP) 2005-03-22 US disclosed
EP-1180520-A1 HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES Institute of Medicinal Molecular Design, Inc. (JP) 2002-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346631-A1 PEPTIDE COMPOSITIONS AND METHODS OF USE VIP, TNFSF10, IAPP RXRA 878/4885RXRB 420/4885RXRG 318/4885
US-12527729-B2 Minoxidil adjuvant therapies RXRA, RXRB, RXRG RXRA 1/4885RXRB 2/4885RXRG 3/4885
US-12533309-B2 Minoxidil adjuvant therapies RXRG, RXRA, RXRB RXRA 2/4885RXRB 3/4885RXRG 1/4885
US-12571046-B2 Methods of detecting and treating multiple system atrophy SYNJ1, MYT1, SYNJ2 RXRA 18/4885RXRB 10/4885RXRG 26/4885
US-20260015352-A1 METHYLTRANSFERASE INHIBITOR AND USE THEREOF EZH2, DOT1L, EHMT1 RXRA 1198/4885RXRB 806/4885RXRG 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.