Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.87 |
| ▸ | HTT | P42858 | 2/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | GHSR | Q92847 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722626 | 0.95 | EPHX1 (0.97) | EPHX1ALDH1A1HTTKDM4ELMNA | |
| SCHEMBL5020899 | 0.93 | EPHX1 (1.00) | EPHX1ALDH1A1HTTKDM4ELMNA | |
| SCHEMBL4138192 | 0.93 | EPHX1 (1.00) | EPHX1ALDH1A1HTTKDM4ELMNA | |
| SCHEMBL422504 | 0.93 | EPHX1 (1.00) | EPHX1ALDH1A1HTTKDM4ELMNA | |
| SCHEMBL11671083 | 0.93 | EPHX1 (1.00) | EPHX1ALDH1A1HTTKDM4ELMNA | |
| SCHEMBL10599308 | 0.93 | EPHX1 (1.00) | EPHX1ALDH1A1HTTKDM4ELMNA | |
| SCHEMBL813735 | 0.93 | EPHX1 (1.00) | EPHX1ALDH1A1HTTKDM4ELMNA | |
| SCHEMBL4603476 | 0.93 | EPHX1 (1.00) | EPHX1ALDH1A1HTTKDM4ELMNA | |
| SCHEMBL17119069 | 0.93 | EPHX1 (1.00) | EPHX1ALDH1A1HTTKDM4ELMNA | |
| SCHEMBL14424453 | 0.90 | EPHX1 (0.72) | EPHX1ALDH1A1HTTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227999-A1 | Heterogeneous Supported Catalytic Carbamate Process | MOLZAHN DAVID C | 2008-09-18 | — | — | US | claimed |
| EP-1943214-A2 | HETEROGENEOUS SUPPORTED CATALYTIC CARBAMATE PROCESS | Dow Gloval Technologies Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007015852-A2 | HETEROGENEOUS SUPPORTED CATALYTIC CARBAMATE PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-02-08 | — | — | WO | claimed |
| CN-119462433-A | Synthesis method of N, N' -disubstituted asymmetric urea and chlorazuron | 内蒙古工业大学 | 2025-02-18 | — | — | CN | disclosed |
| EP-4446310-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | Asahi Kasei Kabushiki Kaisha (JP) | 2024-10-16 | — | — | EP | disclosed |
| CN-118382612-A | Method for producing blocked isocyanate compound and method for producing isocyanate compound | 旭化成株式会社 | 2024-07-23 | — | — | CN | disclosed |
| WO-2024058800-A1 | HIGH DUCTILITY, HIGH MODULUS AND PHTHALATE FREE IMPACT RESISTANT PROPYLENE COPOLYMER | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2023106377-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | 旭化成株式会社 | 2023-06-15 | — | — | WO | disclosed |
| US-20200223871-A1 | Arginase Inhibitors and Methods of Use | ASTRAZENECA AB (SE) | 2020-07-16 | — | — | US | disclosed |
| CN-109843963-A | Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer | 旭化成株式会社 | 2019-06-04 | — | — | CN | disclosed |
| US-20190127395-A1 | Arginase Inhibitors and Methods of Use | ASTRAZENECA AB (SE) | 2019-05-02 | — | — | US | disclosed |
| EP-0507616-A1 | Process for the preparation of trisubstituted ureas by reductive carbonylation | ARCO Chemical Technology, L.P. (US) | 1992-10-07 | — | — | EP | disclosed |
| US-4888321-A | SUBBING AND RECORDING LAYERS EACH CONTAINING HEAT FUSIBLE MATERIAL WITH DEFINED MELTING POINT | FUJI PHOTO FILM CO., LTD. (JP) | 1989-12-19 | — | — | US | disclosed |
| US-4567287-A | Preparation of carbamates from organic carbonates and aromatic ureas | THE UPJOHN CO. (US) | 1986-01-28 | — | — | US | disclosed |
| US-4533929-A | ANIONIC SURFACTANTS AS ANTIFOGGING AGENTS; DIETHYLHEXYL SULFOSUCCINATE | FUJI PHOTO FILM CO., LTD. (JP) | 1985-08-06 | — | — | US | disclosed |
| US-4520377-A | COLOR FORMING LAYER COMO/SED OF ELECTRON DONATING COLORLESS DYE, ELECTRON ACCEPTING COMPOUND, NAPHTHOL UREA AND/OR URETHANE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1985-05-28 | — | — | US | disclosed |
| US-4444863-A | UREA COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |
| US-4401717-A | CONTAINING A CHROMOGEN, A PHENOL LAND A UREA OR CARBAMATE; THERMOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1983-08-30 | — | — | US | disclosed |
| US-4085268-A | Disubstituted s-triazines | ARMSTRONG CORK COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-3936484-A | Production of isocyanates from substituted ureas | ATLANTIC RICHFIELD COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227999-A1 | Heterogeneous Supported Catalytic Carbamate Process | CPS1, CAT, CA7 | EPHX1 4546/4885ALDH1A1 4027/4885HTT 925/4885 |
| US-20200223871-A1 | Arginase Inhibitors and Methods of Use | ARG1, ARG2, NOS2 | EPHX1 687/4885ALDH1A1 407/4885HTT 4776/4885 |
| US-20190127395-A1 | Arginase Inhibitors and Methods of Use | ARG1, ARG2, NOS2 | EPHX1 687/4885ALDH1A1 407/4885HTT 4776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.