Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16994619 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CTSBELANETDP1MAPK1 | |
| SCHEMBL12141748 | 0.84 | ALDH1A1 (0.54) | ALDH1A1CTSBELANETDP1MAPK1 | |
| SCHEMBL19105358 | 0.82 | CTSB (0.61) | ALDH1A1CTSBELANETDP1MAPK1 | |
| SCHEMBL12640200 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CTSBTDP1MAPK1L3MBTL1 | |
| SCHEMBL2928989 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CTSBELANETDP1MAPK1 | |
| SCHEMBL19105400 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CTSBELANETDP1MAPK1 | |
| SCHEMBL2068112 | 0.79 | CTSB (0.58) | ALDH1A1CTSBELANETDP1MAPK1 | |
| SCHEMBL998609 | 0.79 | CTSB (0.58) | ALDH1A1CTSBELANETDP1MAPK1 | |
| SCHEMBL998611 | 0.79 | CTSB (0.58) | ALDH1A1CTSBELANETDP1MAPK1 | |
| SCHEMBL7060350 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CTSBELANETDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178697-B2 | Method for the preparation of atorvastatin and intermediates used therein | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2012-05-15 | — | — | US | disclosed |
| US-20110015407-A1 | METHOD FOR THE PREPARATION OF ATORVASTATIN AND INTERMEDIATES USED THEREIN | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015407-A1 | METHOD FOR THE PREPARATION OF ATORVASTATIN AND INTERMEDIATES USED THEREIN | HMGCR, PCSK9, CETP | ALDH1A1 1340/4885CTSB 1662/4885ELANE 4341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.