Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 6/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749334 | 0.81 | HTR6 (0.50) | CCR2ADRA1DADRA1AADRA1BPTGES2 | |
| SCHEMBL5021127 | 0.80 | HTR6 (0.50) | CCR2ADRA1DADRA1AADRA1BPTGES2 | |
| SCHEMBL5021091 | 0.79 | HTR6 (0.65) | ADRA1DADRA1AADRA1BHTR6ADRA2C | |
| SCHEMBL1748401 | 0.78 | CCR2 (0.49) | CCR2ADRA1DADRA1AADRA1BPTGES2 | |
| SCHEMBL1748828 | 0.76 | HTR6 (0.42) | CCR2ADRA1DADRA1AADRA1BPTGES2 | |
| SCHEMBL1748066 | 0.75 | HTR6 (0.66) | CCR2ADRA1DADRA1AADRA1BPTGES2 | |
| SCHEMBL5321618 | 0.74 | SCN1A (0.44) | CCR2PTGES2HTR6SCN1ASCN5A | |
| SCHEMBL5021157 | 0.74 | CCR2 (0.43) | CCR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1748156 | 0.74 | HTR6 (0.42) | CCR2ADRA1DADRA1AADRA1BPTGES2 | |
| SCHEMBL1748381 | 0.72 | HTR6 (0.48) | CCR2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115850-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS AND METHODS OF TREATMENT | BECKER OREN (IL) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115850-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS AND METHODS OF TREATMENT | HTR6, HTR2A, HTR3B | CCR2 1022/4885PSEN1 3367/4885PSEN2 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.