Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 6/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10280591 | 0.83 | S1PR1 (0.34) | ADRA1A | |
| SCHEMBL1616320 | 0.83 | ADRA1A (0.60) | ADRA1ADRD2DRD3 | |
| SCHEMBL11853960 | 0.78 | ADRA1A (0.54) | ADRA1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL11856738 | 0.77 | ADRA1A (0.53) | ADRA1A | |
| SCHEMBL354140 | 0.73 | ADRA1A (0.58) | ADRA1ADRD2DRD3 | |
| SCHEMBL25248558 | 0.70 | HTR1A (0.53) | ADRA1A | |
| SCHEMBL30510688 | 0.70 | HTR1A (0.53) | ADRA1A | |
| Hydrochloric Acid SCHEMBL30510682 | 0.69 | HTR1A (0.52) | ADRA1A | |
| Hydrochloric Acid SCHEMBL25293937 | 0.69 | HTR1A (0.52) | ADRA1A | |
| SCHEMBL10602964 | 0.68 | CA1 (0.58) | ADRA1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115850-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS AND METHODS OF TREATMENT | BECKER OREN (IL) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115850-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS AND METHODS OF TREATMENT | HTR6, HTR2A, HTR3B | ADRA1A 67/4885DRD2 28/4885DRD3 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.