Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 6/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021157 | 0.88 | CCR2 (0.43) | CCR2ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL1748290 | 0.85 | HTR6 (0.44) | CCR2ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL5021159 | 0.81 | HTR6 (0.58) | HTR6 | |
| SCHEMBL1748381 | 0.77 | HTR6 (0.48) | CCR2ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL1748370 | 0.76 | KMT2A (0.43) | CCR2ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL5321618 | 0.75 | SCN1A (0.44) | CCR2SCN1ASCN5ASCN8ANR1I2 | |
| SCHEMBL1748401 | 0.74 | CCR2 (0.49) | CCR2ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL1749334 | 0.72 | HTR6 (0.50) | CCR2ADRA1DADRA1AADRA1BSCN1A | |
| SCHEMBL5021123 | 0.72 | CCR2 (0.39) | CCR2ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL5021092 | 0.72 | CCR2 (0.47) | CCR2ADRA2AADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115850-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS AND METHODS OF TREATMENT | BECKER OREN (IL) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115850-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS AND METHODS OF TREATMENT | HTR6, HTR2A, HTR3B | CCR2 1022/4885ADRA2A 31/4885ADRA2C 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.