Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664356 | 0.79 | PDE4A (0.33) | ADORA2AADORA2BADORA3PDE4APDE4B | |
| SCHEMBL20866 | 0.79 | ATAD2 (0.41) | PNPATAD2LMNACYP1A2MAPT | |
| SCHEMBL9705280 | 0.79 | PARP1 (0.36) | PARP1PNPADORA2BADORA3PDE4A | |
| SCHEMBL8886026 | 0.77 | PNP (0.35) | PARP1PNPATAD2LMNACYP1A2 | |
| SCHEMBL3259641 | 0.77 | PNP (0.35) | PARP1PNPATAD2LMNACYP1A2 | |
| SCHEMBL8864931 | 0.76 | CDK1 (0.32) | PARP1LMNACYP1A2MAPTADORA2A | |
| SCHEMBL10597939 | 0.76 | PNP (0.33) | PARP1PNPATAD2LMNACYP1A2 | |
| SCHEMBL20576 | 0.76 | PNP (0.34) | PARP1PNPATAD2LMNACYP1A2 | |
| SCHEMBL2051359 | 0.76 | PNP (0.34) | PARP1PNPATAD2LMNACYP1A2 | |
| SCHEMBL2983845 | 0.76 | PNP (0.34) | PARP1PNPATAD2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8172873-B2 | Shape memory polymers | UNIVERSITY OF ROCHESTER (US) | 2012-05-08 | — | — | US | disclosed |
| US-20110251364-A1 | Shape Memory Polymers | NATIONAL SCIENCE FOUNDATION | 2011-10-13 | — | — | US | disclosed |
| US-7935131-B2 | Shape memory polymers | UNIVERSITY OF ROCHESTER (US) | 2011-05-03 | — | — | US | disclosed |
| US-20080177303-A1 | Shape memory polymers | ROCHESTER, UNIVERSITY OF | 2008-07-24 | — | — | US | disclosed |
| US-7268214-B2 | Membrane translocating peptide drug delivery system | MERRION RESEARCH I LIMITED (IE) | 2007-09-11 | — | — | US | disclosed |
| US-20070172516-A1 | Increasing of the resorption of substances via skin and mucous membranes | PROCOM BIOTECHNOLOGISCHE PRODUKTIONS GMBH (DE) | 2007-07-26 | — | — | US | disclosed |
| EP-1534315-A2 | INCREASING OF THE RESORPTION OF SUBSTANCES VIA SKIN AND MUCOUS MEMBRANES | PROCOM BIOTECHNOLOGISCHE PRODUKTION GMBH (DE) | 2005-06-01 | — | — | EP | disclosed |
| US-6780846-B1 | WHICH ENHANCE UPTAKE OF A PHARMACEUTICALLY ACTIVE AGENT INTO A CELL, INTO OR OUT OF AN INTRACELLULAR COMPARTMENT, AND ACROSS A CELL LAYER | ELAN CORPORATION, PLC (IE) | 2004-08-24 | — | — | US | disclosed |
| US-20040138132-A1 | Membrane translocating peptide drug delivery system | MERRION RESEARCH III LIMITED (IE) | 2004-07-15 | — | — | US | disclosed |
| WO-2004022657-A2 | INCREASING OF THE RESORPTION OF SUBSTANCES VIA SKIN AND MUCOUS MEMBRANES | PROCOM BIOTECHNOLOGISCHE PRODUKTIONS GMBH (DE) | 2004-03-18 | — | — | WO | disclosed |