Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20576 | 0.81 | PNP (0.34) | PNPPARP1ABL1RIN1ATAD2 | |
| SCHEMBL2051359 | 0.81 | PNP (0.34) | PNPPARP1ABL1RIN1ATAD2 | |
| SCHEMBL6168437 | 0.81 | PNP (0.34) | PNPPARP1ABL1RIN1ATAD2 | |
| SCHEMBL1828928 | 0.81 | PNP (0.34) | PNPPARP1ABL1RIN1ATAD2 | |
| SCHEMBL20866 | 0.81 | ATAD2 (0.41) | PNPATAD2LMNACYP1A2MAPT | |
| SCHEMBL9960806 | 0.79 | PNP (0.38) | PNPPARP1ABL1RIN1LMNA | |
| SCHEMBL7812591 | 0.78 | ABL1 (0.33) | PNPPARP1ABL1RIN1 | |
| SCHEMBL10597939 | 0.78 | PNP (0.33) | PNPPARP1ATAD2LMNACYP1A2 | |
| SCHEMBL1301996 | 0.78 | PNP (0.33) | PNPPARP1 | |
| SCHEMBL874734 | 0.77 | ADORA2A (0.45) | PNPCYP1A2ADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631259-A | PURINE BASE DERIVATIVES FOR NUCLEOSIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |