Sugi Predict

Sugi Predict / Compounds / SCHEMBL502192

SCHEMBL502192

SCHEMBL502192

[CH2]Cc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 4/20 0.59
▸ RAB9A P51151 4/20 0.59
▸ LMNA P02545 2/20 0.59
▸ KDM4E B2RXH2 7/20 0.38
▸ POLB P06746 5/20 0.38
▸ HPGD P15428 5/20 0.38
▸ ALDH1A1 P00352 5/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ MAPT P10636 3/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ USP2 O75604 1/20 0.33
▸ IDH1 O75874 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.32
▸ KCNMA1 Q12791 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9149045 0.88 NPC1 (0.56) NPC1RAB9ALMNAKDM4EPOLB
SCHEMBL11892463 0.87 RAB9A (0.63) NPC1RAB9ALMNAKDM4EPOLB
SCHEMBL30240912 0.85 NPC1 (0.61) NPC1RAB9ALMNAKDM4EPOLB
SCHEMBL76414 0.85 NPC1 (0.61) NPC1RAB9ALMNAKDM4EPOLB
SCHEMBL29046139 0.85 NPC1 (0.54) NPC1RAB9ALMNAKDM4EPOLB
SCHEMBL9552011 0.84 NPC1 (0.59) NPC1RAB9ALMNAKDM4EPOLB
SCHEMBL2796744 0.84 NPC1 (0.59) NPC1RAB9ALMNAKDM4EPOLB
SCHEMBL29636784 0.84 NPC1 (0.64) NPC1RAB9ALMNAKDM4EPOLB
SCHEMBL940379 0.84 NPC1 (0.64) NPC1RAB9ALMNAKDM4EPOLB
SCHEMBL1263646 0.83 NPC1 (0.55) NPC1RAB9ALMNAKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4341324-A1 BIOSTABLE POLYMER BRUSHES WITH DEFINED VISCOSITY AND OPTICAL PROPERTIES FOR USE IN A NOVEL INTRAOCULAR LENS Duke University (US) 2024-03-27 — — EP claimed
EP-3699676-B1 METHOD FOR MANUFACTURING OPHTHALMIC LENS IN WHICH MEMBER IS EMBEDDED SEED CO LTD (JP) 2024-04-10 — — EP disclosed
CN-117413217-A Photochromic contact lenses with color beautification 爱尔康公司 2024-01-16 — — CN disclosed
EP-3823811-B1 PRODUCTION OF MOLDED BODIES FROM AN INORGANIC-ORGANIC HYBRID POLYMER WITH HIGH RESOLUTION USING 3D PRINTING, MOLDED BODIES WITH A HIGH FLEXURAL STRENGTH AND ELASTIC MODULUS, AND THE USE THEREOF FOR DENTAL PURPOSES FRAUNHOFER GES FORSCHUNG (DE) 2023-11-08 — — EP disclosed
CN-116535961-A Antifogging agent composition and antifogging product having antifogging coating film 日油株式会社 2023-08-04 — — CN disclosed
US-20230151229-A1 INFRARED CUT FILTER, SOLID-STATE IMAGE SENSOR FILTER, SOLID-STATE IMAGE SENSOR, AND METHOD OF PRODUCING SOLID-STATE IMAGE SENSOR TOPPAN INC. (JP) 2023-05-18 — — US disclosed
EP-4177279-A1 INFRARED BLOCKING FILTER, FILTER FOR SOLID-STATE IMAGING ELEMENT, SOLID-STATE IMAGING ELEMENT, AND METHOD FOR PRODUCING FILTER FOR SOLID-STATE IMAGING ELEMENT TOPPAN INC. (JP) 2023-05-10 — — EP disclosed
US-11618211-B2 Production of molded bodies from an inorganic-organic hybrid polymer with high resolution using 3D printing, molded bodies with a high flexural strength and elastic modulus, and the use thereof for dental purposes FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2023-04-04 — — US disclosed
CN-115769114-A Infrared light cut filter, filter for solid-state imaging element, and method for manufacturing filter for solid-state imaging element 凸版印刷株式会社 2023-03-07 — — CN disclosed
WO-2023012058-A1 DENTAL IMPLANT MESOSTRUCTURES HAVING A SHAPE MEMORY EFFECT Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-02-09 — — WO disclosed
US-7468397-B2 Polymerizable siloxane-quaternary amine copolymers BAUSCH & LOMB INCORPORATED (US) 2008-12-23 — — US disclosed
EP-1926367-A1 STABILIZATION OF IODINE BIOCIDES Lanxess Deutschland GmbH & Co.KG (DE) 2008-06-04 — — EP disclosed
US-20080001318-A1 Polymerizable siloxane-quaternary amine copolymers VALEANT PHARMACEUTICALS NORTH AMERICA LLC 2008-01-03 — — US disclosed
WO-2007028527-A1 STABILIZATION OF IODINE BIOCIDES LANXESS DEUTSCHLAND GMBH (DE) 2007-03-15 — — WO disclosed
US-20060078754-A1 Optical film, polarizing plate and display KONICA MINOLTA OPTO, INC. (JP) 2006-04-13 — — US disclosed
EP-1509807-A4 HIGH REFRACTIVE INDEX, OPTICALLY CLEAR AND SOFT HYDROPHOBIC ACRYLAMIDE COPOLYMERS STAAR SURGICAL CO (US) 2005-08-31 — — EP disclosed
EP-1509807-A1 HIGH REFRACTIVE INDEX, OPTICALLY CLEAR AND SOFT HYDROPHOBIC ACRYLAMIDE COPOLYMERS Staar Surgical Company (US) 2005-03-02 — — EP disclosed
WO-2003102672-A1 HIGH REFRACTIVE INDEX, OPTICALLY CLEAR AND SOFT HYDROPHOBIC ACRYLAMIDE COPOLYMERS STAAR SURGICAL COMPANY (US) 2003-12-11 — — WO disclosed
EP-1090313-A1 METHOD FOR MAKING CONTACT LENSES HAVING UV ABSORBING PROPERTIES BAUSCH & LOMB INCORPORATED (US) 2001-04-11 — — EP disclosed
WO-1999060428-A1 METHOD FOR MAKING CONTACT LENSES HAVING UV ABSORBING PROPERTIES BAUSCH & LOMB INCORPORATED (US) 1999-11-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080001318-A1 Polymerizable siloxane-quaternary amine copolymers SRM, PARG, PARN NPC1 4629/4885RAB9A 2916/4885LMNA 2362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.