SCHEMBL502194

SCHEMBL502194

CCOC(=O)C(C#N)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
GAA P10253 2/20 0.61
MMP8 P22894 1/20 0.51
TSHR P16473 2/20 0.48
PIN1 Q13526 1/20 0.47
NPC1 O15118 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 2/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27920341 0.98 SMN1; SMN2 (0.60) SMN1; SMN2MEN1KMT2AGAAMMP8
SCHEMBL17466005 0.91 MEN1 (0.58) SMN1; SMN2MEN1KMT2AGAAMMP8
SCHEMBL5299951 0.91 SMN1; SMN2 (0.56) SMN1; SMN2MEN1KMT2AGAAMMP8
SCHEMBL6289274 0.86 SMN1; SMN2 (0.54) SMN1; SMN2MEN1KMT2AGAAMMP8
SCHEMBL7358766 0.85 MEN1 (0.50) SMN1; SMN2MEN1KMT2AGAAMMP8
SCHEMBL11167719 0.84 PTGS1 (0.52) SMN1; SMN2MEN1KMT2AGAAMMP8
SCHEMBL11216621 0.84 PTGS1 (0.52) SMN1; SMN2MEN1KMT2AGAANPC1
SCHEMBL8071744 0.84 MMP8 (0.53) SMN1; SMN2MEN1KMT2AGAAMMP8
SCHEMBL28739410 0.83 ALDH1A1 (0.49) SMN1; SMN2MEN1KMT2AGAATSHR
SCHEMBL5081149 0.83 SMN1; SMN2 (0.51) SMN1; SMN2MEN1KMT2AGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 766 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435181-B2 Formulations capable of reacting with or removal of molecular oxygen LI SHENSHEN (US) 2025-10-07 US disclosed
EP-3745105-B1 TEMPERATURE DETECTION LABEL AND ARTICLE MANAGEMENT DEVICE USING SAME HITACHI LTD (JP) 2025-08-27 EP disclosed
EP-3440045-B1 PREVENTION, TREATMENT AND REVERSAL OF DISEASE USING THERAPEUTICALLY EFFECTIVE AMOUNTS OF DICARBOXYLIC ACID COMPOUNDS UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2025-08-20 EP disclosed
EP-4524129-A1 METHOD FOR PREPARING 2-SUBSTITUTED ARYL ACETONITRILE COMPOUND AND USE THEREOF Maxunitech Inc. (CN) 2025-03-19 EP disclosed
US-20250059132-A1 METHOD FOR PREPARING 2-SUBSTITUTED ARYLACETONITRILE COMPOUND AND APPLICATION THEREOF MAXUNITECH INC (CN) 2025-02-20 US disclosed
US-12227501-B2 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as CSNK1 inhibitors BAYER AKTIENGESELLSCHAFT (DE) 2025-02-18 US disclosed
US-20240400247-A1 TEMPERATURE INDICATOR MANUFACTURING SYSTEM AND TEMPERATURE INDICATOR MANUFACTURING METHOD HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) 2024-12-05 US disclosed
EP-4431889-A1 TEMPERATURE INDICATOR MANUFACTURING SYSTEM AND TEMPERATURE INDICATOR MANUFACTURING METHOD Hitachi Industrial Equipment Systems Co., Ltd. (JP) 2024-09-18 EP disclosed
US-12085452-B2 Temperature detection ink, temperature detection ink initialization method, temperature indicator, and article management system HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) 2024-09-10 US disclosed
WO-2024142146-A1 TEMPERATURE INDICATOR AND METHOD FOR PRODUCING TEMPERATURE INDICATOR 株式会社日立産機システム 2024-07-04 WO disclosed
US-4923792-A BENZYLIDENE LEUCO COMPOUNDS AS COLOR-GENERATING REDUCING AGENTS, TOPCOAT OF POLYVINYL ALCOHOL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-08 US disclosed
US-4883747-A LIGHT SENSITIVE SILVER HALIDE, ORGANIC ACID SILVER SALT, LEUCO DYE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-11-28 US disclosed
EP-0294099-A2 Colour photothermographic elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-12-07 EP disclosed
US-4438041-A FROM A CYANOACETALDEHYDE ACETAL, HYDROXYLAMINE, AND AN ALCOHOL UBE INDUSTRIES, LTD. (JP) 1984-03-20 US disclosed
US-RE30420-E DIURETIC, HYPOTENSIVE BAYER AKTIENGESELLSCHAFT (DE) 1980-10-21 US disclosed
US-4112227-A DIURETIC, SALURETIC, ANTIHYPERTENSIVE, ANTITHROMBOTIC BAYER AKTIENGESELLSCHAFT (DE) 1978-09-05 US disclosed
US-4056533-A HYPOTENSIVE AGENTS, ANTICOAGULANTS, DIURETICS BAYER AKTIENGESELLSCHAFT (DT) 1977-11-01 US disclosed
US-4000294-A DIURESIS OR SALURESIS BAYER AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed
US-3992404-A DIURETICS, SALURETICS, ANTIHYPERTENSIVE AGENTS, AND ANTITHROMBOTIC AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-16 US disclosed
US-3952008-A DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250059132-A1 METHOD FOR PREPARING 2-SUBSTITUTED ARYLACETONITRILE COMPOUND AND APPLICATION THEREOF CYP1B1, CYP1A2, CYP2C9 SMN1; SMN2 2364/4885MEN1 678/4885KMT2A 1842/4885
US-12227501-B2 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as CSNK1 inhibitors CSNK1A1, CSNK1G1, CSNK1E SMN1; SMN2 2465/4885MEN1 3195/4885KMT2A 1912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.