Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26016432 | 1.00 | MEN1 (0.44) | MEN1KMT2AHTR2CHSD11B1CYP19A1 | |
| SCHEMBL28957039 | 0.84 | HTR2C (0.47) | MEN1KMT2AHTR2CHSD11B1CYP19A1 | |
| SCHEMBL28957041 | 0.84 | HTR2C (0.47) | MEN1KMT2AHTR2CHSD11B1CYP19A1 | |
| SCHEMBL29698141 | 0.84 | HTR2C (0.47) | MEN1KMT2AHTR2CHSD11B1CYP19A1 | |
| SCHEMBL20845751 | 0.81 | KDM1A (0.41) | MEN1KMT2AHTR2CALDH1A1 | |
| SCHEMBL30669254 | 0.81 | GRM5 (0.42) | MEN1KMT2ACYP19A1MAOBALDH1A1 | |
| SCHEMBL10242047 | 0.81 | SLC6A3 (0.51) | SLC6A2ALDH1A1 | |
| SCHEMBL2899075 | 0.81 | KDM1A (0.41) | MEN1KMT2AHTR2CALDH1A1 | |
| SCHEMBL5021614 | 0.81 | GRM5 (0.42) | MEN1KMT2ACYP19A1MAOBALDH1A1 | |
| SCHEMBL5021243 | 0.80 | LMNA (0.54) | MEN1KMT2AHTR2CCYP19A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |