Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28957041 | 1.00 | HTR2C (0.47) | HTR2CHSD11B1MEN1KMT2ACYP19A1 | |
| SCHEMBL28957039 | 1.00 | HTR2C (0.47) | HTR2CHSD11B1MEN1KMT2ACYP19A1 | |
| SCHEMBL26016432 | 0.84 | MEN1 (0.44) | HTR2CHSD11B1MEN1KMT2ACYP19A1 | |
| SCHEMBL5021997 | 0.84 | MEN1 (0.44) | HTR2CHSD11B1MEN1KMT2ACYP19A1 | |
| SCHEMBL5129073 | 0.84 | LMNA (0.41) | HTR2CHSD11B1 | |
| SCHEMBL4319758 | 0.84 | LMNA (0.41) | HTR2CHSD11B1 | |
| SCHEMBL1705219 | 0.80 | MAOB (0.42) | HSD11B1CYP19A1MAOB | |
| SCHEMBL13950143 | 0.80 | MAOB (0.42) | HSD11B1CYP19A1MAOB | |
| SCHEMBL14521456 | 0.80 | MAOB (0.42) | HSD11B1CYP19A1MAOB | |
| SCHEMBL29576218 | 0.76 | HSD11B1 (0.48) | HTR2CHSD11B1MEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605272-B | Preparation method of (R) -fluoxetine and derivatives thereof | 中国科学技术大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-114605272-A | Preparation method of (R) -fluoxetine and derivative thereof | 中国科学技术大学 | 2022-06-10 | — | — | CN | disclosed |