Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL5492575 | 0.84 | TSHR (0.35) | DDB1CRBNTSHRGAAPKLR | |
| SCHEMBL845434 | 0.69 | CRBN (0.57) | DDB1CRBNTSHRTDP1ALDH1A1 | |
| Thalidomide SCHEMBL30511827 | 0.68 | CRBN (0.67) | DDB1CRBNTSHRTDP1ALDH1A1 | |
| SCHEMBL3125601 | 0.66 | CRBN (0.55) | DDB1CRBNTSHRTDP1ALDH1A1 | |
| SCHEMBL18263933 | 0.66 | CRBN (0.55) | DDB1CRBNTSHRTDP1ALDH1A1 | |
| SCHEMBL22845492 | 0.64 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL2065573 | 0.62 | CRBN (0.65) | DDB1CRBNTSHRTDP1ALDH1A1 | |
| SCHEMBL31013981 | 0.62 | CRBN (0.65) | DDB1CRBNTSHRTDP1ALDH1A1 | |
| SCHEMBL31013928 | 0.62 | CRBN (0.65) | DDB1CRBNTSHRTDP1ALDH1A1 | |
| SCHEMBL22845479 | 0.60 | DDB1 (0.49) | DDB1CRBNTSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080226601-A1 | Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods | UNIVERSITY OF ROCHESTER (US) | 2008-09-18 | — | — | US | disclosed |
| EP-1903873-A2 | HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS | THE UNIVERSITY OF ROCHESTER (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006135602-A2 | HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS | UNIVERSITY OF ROCHESTER (US) | 2006-12-21 | — | — | WO | disclosed |